Carcinoid Tumor

Question 1

Origin

Answer 1

Neuroendocrine organs like endocrine pancreas

Question 2

Site

Answer 2

GI tract = small intestine (appendix) =40% (major site)
Stomach
Trachea bronchial tree and lungs

Question 3

Morphology

Answer 3

Intramural masses
Yellow/ tan colour
Very firm

Question 4

Microscopy

Answer 4

Uniform cells:- islands, glands sheets
Cells have scant pink cytoplasm
Anaplasia
Mitotic activity

Question 5

IHC strain

Answer 5

Chromogramin A

Question 6

If carcinoid tutor produce gastin

Answer 6

Zollinger Ellison syndromes

Question 7

If carcinoid tutor from ileum

Answer 7

Carcinoid syndrome

Question 8

Carcinoid syndromes secrete

Answer 8

Vasoactive amines

Question 9

Why vasoactive amines should be released to non-postal veins circulation to produce carcinoid syndrome?

Answer 9

As liver metabolizes them to inactive forms

Question 10

Clinical features of carcinoid syndrome

Answer 10

Flushing of skin
Sweating
Bronco spasm
Abdominal pain
Diarrhea

Question 11

Foregut carcinoid tutor

Answer 11

Stomach, duodenum, esophagues

Question 12

Midgut carcinoid tutor

Answer 12

Jejunum, ileum

Question 13

Hindgut carcinoids

Answer 13

Appendix, rectal carcinoids

Question 14

Carcinoid syndrome develops with metastasis to

Answer 14

Liver or lungs