Carcinogens Flashcards

1
Q

Aflatoxins (Aspergillus)

A

Liver

Hepatocellular carcinoma

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2
Q

Alkylating agents

A

Blood

Leukemia/lymphoma

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3
Q

Aromatic amines (benzidine, 2-naphthylamine)

A

Bladder

Transitional cell carcinoma

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4
Q

Arsenic

A

Liver, lung, skin

Angiosarcoma, Lung cancer, squamous cell carcinoma

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5
Q

Asbestos

A

Lung

Bronchogenic carcinoma > mesothelioma

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6
Q

Carbon tetrachloride

A

Liver

Centrilobular necrosis, fatty change

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7
Q

Cigarette smoke

A
Bladder --> transitional cell carcinoma
Esophagus --> SCC/Adenocarcinoma
Kidney --> RCC
Larynx --> SCC
Lung --> SCC and Small cell carcinoma
Pancreas --> Pancreatic adenocarcinoma
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8
Q

Ethanol

A

Liver –> Hepatocellular carcinoma

Esophagus –> SCC

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9
Q

Ionizing radiation

A

Thyroid

Papillary thyroid carcinoma

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10
Q

Nitrosamines (smoked foods)

A

Stomach

Gastric cancer

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11
Q

Radon

A
Lung
Lung cancer (2nd leading cause after smoking)
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12
Q

Vinyl chloride

A

Liver

Angiosarcoma

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