Carbon monoxide poisoning Flashcards
Sources of carbon monoxide:
1) Gasoline
2) Exhaust fumes
3) Diesel
4) Propane powered engines
5) Charcoal fire smoke
6) Methylene chloride
7) Tobacco smoke
When is the peak time for carbon monoxide poisoning?
6-10pm
What are the peak months for carbon monoxide poisoning?
December and January (non-fire)
Most common setting for carbon monoxide poisoning?
At home
How does carbon monoxide work?
Reversibly binds hemoglobin = functional anemia
Small concentrations of carbon monoxide can result in significant ___.
Carboxyhemoglobin (HbCO)
Carbon monoxide shifts the oxygen-hemoglobin dissociation curve to the __.
Left
What is the Bohr effect?
Oxygen and carbon monoxide binding is inversely proportional
What are the body systems most affected by carbon monoxide poisoning?
1) CVS
2) CNS
What are the signs and symptoms of carbon monoxide poisoning? (HbCO: 5-20%)
Mild severity:
1) Asymptomatic
2) Headache
3) Shortness of breath
4) Nausea and vomiting
5) Dizziness
6) Blurred vision
What are the signs and symptoms of carbon monoxide poisoning? (HbCO: 21-40%)
Moderate severity:
1) Worsening headache
2) Confusion
3) Syncope
4) Chest pain
5) Dyspnea
6) Tachycardia
7) Tachypnea
8) Weakness
What are the signs and symptoms of carbon monoxide poisoning? (HbCO: 41-60%)
Severe:
1) Dysrhythmias
2) Palpitations
3) Cardiac ischemia
4) Confusion
5) Respiratory arrest
6) Pulmonary edema
7) Seizures
8) Coma
9) Cardiac arrest
What are the long term cardiovascular effects of carbon monoxide poisoning?
1) Myocardial injury from hypoxia and cellular damage
2) Premature death
What are the factors increasing myocardial injury risk in carbon dioxide poisoning?
1) Male
2) History of hypertension
3) GCS < 14 when the patient was first found
What are the long term neurological effects of carbon monoxide poisoning?
Delayed onset neurobehavioral dysfunction (CO-induced delayed neuropsychiatric syndrome)