Carbon Dioxide Transport in the Blood

Question 1

What are the three form in which carbon dioxide is transported in the blood (in decreasing prevalence)?

Answer 1

Bicarbonate - 60%
Carbamino compounds - 30%
In solution - 10%

Question 2

How does carbon dioxide’s solubility relate to that of oxygen?

Answer 2

CO2 is approx. 20x more soluble than oxygen

Question 3

Where is bicarbonate formed?

Answer 3

In red blood cells

Question 4

How does bicarbonate enter the plasma?

Answer 4

Exchange with chloride

Question 5

How are carbamino compounds formed?

Answer 5

By combining carbon dioxide with the terminal amino groups in blood proteins

Question 6

How carbamino-haemoglobin formed?

Answer 6

Combination of the “globin” of haemoglobin and a carbamino

Question 7

How does the Halden effect relate to Hb’s affinity for CO2 and CO2-generated hydrogen ions?

Answer 7

Removing oxygen form Hb increases the ability of Hb to pick up carbon dioxide and CO2-generated hydrogen ions

Question 8

The Bohr and Haldane effect work together to facilitate ______ (3)?

Answer 8

Oxygen liberation
Carbon dioxide uptake
CO2-generated hydrogen ion uptake

Question 9

What has to happen to bicarbonate before exhalation?

Answer 9

Has to be converted back to carbon dioxide to be exhaled

Question 10

At any partial pressure there will be ___ CO2 in mixed venous blood

Answer 10

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