carbohydrates Flashcards

1
Q

name 3 dissacharides

A

lactose , sucrose , maltose

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2
Q

what is another name for sugar

A

hexoses
(type of monosaccarhide rememeber

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3
Q

what are heteropolysaccharides and homopolysacchardies

A

hetero- carbohydrate with two or more monomers

homo-carbohydrate with one monomer

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4
Q

what is the most common disaccharide deficiency.

A

lactose deficiency

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5
Q

identify the initial, middle and final location of carbohydrate absoportion in the body and where u can identify which enzymes are involved in each step

A

initial- mouth (by amylase)

middle- doudenum (pancreatic amylase)

final - jejunum

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6
Q

What mechanism allows glucose to move in to/be absorbed by epithelial cells?

A

glucose/Na symport

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7
Q

what is glucose phosphorylated into immediately after absoprtion

A

glucose-6-phosphate

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8
Q

what CELL helps with the phopsorylation of glucose immediately after absoprtion?

A

hepatocytes

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9
Q

which enzymes catalyse glucose phophoryalting into G-6-P

A

hexokinase (present in all tissue)

glucokinase (in the liver )

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10
Q

what is the inverse of having a high Km value

A

low affinity

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11
Q

State whether glucokinase and hexokinase have high or low Km and Vmax values,

A

glucokinase -high km(low affinity) and high
Vmax

hexokinase - low Km (high affinity & low Vmax, inefficient enzyme(breaks down slowly) with high affinity for glucose (can obtain glucose in low conc)

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11
Q

what type of pathway is glycolysis - anabolic or catabolic ?

A

catabolic pathway

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12
Q

What is meant by substrate level phosphorylation?

A

formation of ATP from ADP

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13
Q

what electron is vital for glycolysis to occur ?

A

NAD+

NAD+ becomes NADH

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14
Q

Identify the term used to describe the regeneration of NAD+ (using pyruvate into lactate) after glycolysis so that the cycle can start again.

A

redox balance

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15
Q

what is the purpose of gluceogenesis ?

A

generate glucose from NON-carbohydrate molecules

16
Q

Name a substance that each fructose and galactose can be converted into to be used in glycolysis.

A

fructose - F-6-P

galactose- G-6-P

17
Q

what does having a high Vmax mean to the enzyme

A

means enzyme is effiecient and breaks substance down fast

18
Q

going from G-6-P TO F-6-P use what catalyst enzyme ?

A

phosphohexose

19
Q

be familiar with 4 things pyruvate can be converted into

A

ehtanol, lactate , aceytl Coa and Co2

20
Q

is the reaction between G-6-P and F-6-P reversible or not?

A

it is reverisble

glucose to -G-6-P is irreversible

the F reactions are irreversible
(F-6-P –> F-1,6BP)

21
Q

what can G-6-P be stored as?

A

glycogen

22
Q

what is the central enzyme of glycogen that starts off the process of formation?

A

glucogenin

23
Q

what causes Gierkes disease?

A

G-6-P defieciency

24
Q

what are the 2 stages of glycolysis?

A
  1. prepatory phase

2.pay off phase

25
Q

3rd step of glycolysis is catalysed by which enzyme?

A

3rd step is F-6-P to F,1,6-P

using phophofructokinase-1

26
Q

which 2 steps does the ATP–>ADP transfer occur in glycoylsis ?

A

step 1 and step 3

27
Q

NAD+ is essential for glycolysis, how is this regenarated?

A

pyruvate converted into lactate

28
Q

in the presence of oxygen, pyruvate is oxidised into what?

A

Aceytl CoA

29
Q

what is F-1,6-BP converted into?

A

DHAP

30
Q

what does glycoysis produce?

A

2 PYRUVATE

2 ATP (starts with 4)

2 NADH

31
Q

how many ATP does glyoclysis start with and how many does it end with

A

starts -4

end with 2

32
Q

ultimately what does glucose in glycolysis want to be converted into at the end?

A

2 PYRUVATE

33
Q

is glycolysis an anaorobic or aeorbic process?

A

anaeorobic

(pyruvate converted into lactate to regenerate NAD+)