Carbohydrate metabolism Flashcards
Glycolysis
Break down of carbohydrates into simple sugars, leading to the production of pyruvate
acetyl CoA production
decarboxylation and reduction of pyruvate
Oxidative phosphorylation
TCA cycle produces reduced co-factors which are re-oxidised by the electron transport chain which in turn is coupled to ATP production
Glycogen production
Excess glucose-6-phosphate used in liver + muscle
Fatty acid production
Excess acetyl CoA, stored as triglycerides in adipose tissue
Fasting
Much of the acetyl CoA results in ketone body formation instead of entering the TCA cycle
Nucleotide production (amino acid source)
Backbone of pyruvate and other TCA cycle intermediates
Pentose phosphate pathway
Glucose-6-phosphate used as a source for nucleotide production in a pathway that generates the bulk of the NADPH needed for anabolic pathways