Carbapenems

Question 1

Names

Answer 1

Meropenem, imipenem/cilastatin, doripenema, and ertapenem

Question 2

MOA

Answer 2

Inhibi synthese in the bacterial cell wall

Question 3

Pharmacokinetics

Answer 3

Meropenem is approved by the FDA for treatment of intraabdominal infections, skin and skin structure infections, and meningitis in patients older than 3 months of age

Question 4

Side effects

Answer 4

N/V, phlebitis at the infusion site, elevation of liver enzymes, and leukopenia. Seizure may occur. Should be used with caution on patients allergic to penicillins

Question 5

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