Carbapenems Flashcards

B-lactam ring, bactericidal, cell wall synthesis

1
Q

Mechanism

A

Bactericidal

Inhibit cell wall synthesis

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2
Q

Spectrum

A

Broadest spectrum of all b lactam antibiotics
Most G -ve cocci
Gram -ve bacilli
Anaerobes

Can resist destruction by most B lactamses

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3
Q

Indications

A
Drug resistant severe infections
UTIs
Lower respiratory infection
Intra abdominal infection
Gynecological infections
Skin soft tissue infections
Joint infections
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4
Q

Side effects

A
Nausea vomiting diarrhea
Pseudomembranous colitis
Seizure
dizziness 
hypotension
Hypersensitivity
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