Carbapenems Flashcards
B-lactam ring, bactericidal, cell wall synthesis
1
Q
Mechanism
A
Bactericidal
Inhibit cell wall synthesis
2
Q
Spectrum
A
Broadest spectrum of all b lactam antibiotics
Most G -ve cocci
Gram -ve bacilli
Anaerobes
Can resist destruction by most B lactamses
3
Q
Indications
A
Drug resistant severe infections UTIs Lower respiratory infection Intra abdominal infection Gynecological infections Skin soft tissue infections Joint infections
4
Q
Side effects
A
Nausea vomiting diarrhea Pseudomembranous colitis Seizure dizziness hypotension Hypersensitivity