Carbamazepine OD

Question 1

standard dose of AC

Answer 1

50 g PO

Question 2

List 5 general contraindications for AC

Answer 2

1- subtoxic dose 
2- uncooperative patient 
3-active vomiting 
4- ingestion non bound to AC 
5- Out the time frame for binding

Question 3

List the expected clinical features for a significant carbamazepine OD

Answer 3

1- CNS depression
2- seizure
3- hypotension ( Wide QRS , and first degree HB )
4- Urinary retention + ileus ( anticholinergic )

Question 4

30 year F , Wt 90 Kg , P/W polypharmacy OD ( panadeine forte , carbamazeppine, and temazepam ) ,
During your Mx , she developed tonic-clonic seizure , List 4 conditions that should be excluded ?

Answer 4

1-Bhcg 
2- underlying seizure disorder 
3- Alcohol withdrawal 
4- ICH 
5- Metabolic : hypoglycemia , hyponatremia 
6- sepsis

Question 5

list methods of decontamination or elimination

Answer 5

1- AC ( early presentation , if ingestion <50 mg/kg ) but if >50mg/kg then intubated and AC
2- MADC ( BS present before given it )
3- ECMO ( prolonged coma >48/24 , HD instability