Capillary Dynamics/ Lymphatics Flashcards
What are the characteristics of capillaries?
One cell layer thick, surrounded by lipid membrane, large surface area, slow blood flow
What are the three types of capillaries?
Continuous, Fenestrated, Discontinuous
What is the primary method of transport into/out of capillaries?
Diffusion
What factors affect diffusion?
Concentration gradient, properties of solute and barrier, distance, and surface area
What factors affect bulk flow?
Hydrostatic pressures and oncotic pressure
What is the pushing force of capillary dynamics?
Hydrostatic pressure
What is the pulling force of capillary dynamics?
Oncotic force
What term describes fluid leaving the capillary? Entering the capillary?
Filtration; Reabsorbtion
What is the primary factor for reabsorption?
Oncotic pressure in capillaries
What is the primary factor for filtration?
Hydrostatic pressure in capillaries
Where within the capillary is capillary hydrostatic pressure the lowest?
Venous end
On what end of the capillary does more reabsorbtion take place?
Venous end
What determines the hydrostatic pressure within capillaries?
Arterioles
What is the effect of decreasing arteriole resistance on capillary hydrostatic pressure?
Increased hydrostatic pressure
What is the effect of decreasing compliance on venous hydrostatic pressure?
Increases hydrostatic pressure
What is the equation for Starling forces?
Q=K((Pc -Pif) - reflection coefficient (capillary oncotic pressure -interstitial fluid oncotic pressure))
What does the capillary filtration coefficient (K) respresent?
Permeability of capillary barrier
What does the reflection coeeficient (sigma) represent?
Impediment of protein movement across the barrier
What might increase the interstitial fluid oncotic pressure?
Leak of proteins into the interstitial fluid
An increased interstitial fluid hydrostatic pressure would have what effect on lymphatics?
Increased lymphatic volume
