CAP 3 Flashcards
What psychiatric condition are patients with velocardiofacial syndrome more at risk of?
Schizophrenia
When is breast cancer screening done?
50-70 every 3 years
When is bowel cancer screening done?
50-74 every 2 years in Scotland
When is diabetic eye screen done?
In diabetic patients over 12 every year
What is galanatamine?
Cholinesterase inhibitor
What artery is at risk in lateral abdominal port?
Inferior epigastric
What artery is anatomically close to lower end of ureter?
Uterine artery
How is hep A spread?
Fecal oral
What is the first area affected in alzheimers?
Nucleus baseless of meynert
What is the feature of early stage diabetic nephropathy?
Proteinuria
What is p53 and why is it important?
It is a tumour suppressor - if it mutates if may not function in cancer
At what stage does an embryo implant?
Blastocyst
What happens to Blood pressure in pregnancy?
Decreases in 2nd trimester - returns to normal in 3rd
What happens to CO and GFR in pregnancy?
Increase by 30-50%
What happens to vital capacity in pregnancy?
Nothing
What does of folic acid should obese women take?
5mg
What is the difference between dystonia and tardive dyskinesia in terms of time?
Dystonia - onset in hours
TD - onset in years
What nerve root is responsible for leg extension, patellar reflex and ankle dorsiflexion?
L4
How is wilsons disease inherited?
Autosomal recessive
What might a green nipple discharge indicate?
Duct ectasia
What condition might trauma to the breast cause?
Fat necrosis
What might cause a hot tender breast in an elderly woman?
Inflammatory breast cancer
What sort of organism is treponema palladium?
Spirochaete
What may happen to phosphate in CKD?
Rise
What is seen in urine in UTI - nitrates or nitrites?
Nitrites
What other condition is polycystic kidney disease associated with?
Subarachnoid haemorrhage
What is the most abundant antibody?
IgG
Which antibody is found in breast milk?
IgA
Which antibody is pentameric?
IgM
What volume of urine in the bladder causes a desire to void?
250mls
Parasympathetic or sympathetic, what causes contraction of detrusor muscle?
Para
Name an antibiotic contraindicated in breast feeding?
Tetracycline
What is the treatment for gonorrhoea?
Azithromycin and ceftriaxone
Which area is affected in receptive aphasia?
Wernickes
Which area is affected in expressive aphasia?
Broccas
Which area is affected in nominal aphasia?
Angular gyrus
Which artery supplies the midgut?
Superior mesenteric
What condition causes a raised CA125?
Ovarian cancer
What nerve causes biceps reflex?
C5/6
What nerve causes ankle reflex?
S1
What nerve causes knee reflex?
L3/4
What sort of glomerulonephritis may occur in a young patient after an URTI?
IgA nephropathy
What is the first step management for asthma?
Inhaled short acting beta 2 agonist as required
What is step 2 in asthma management?
Add inhaled corticosteroid
What is step 3 in asthma management?
Add inhaled long acting beta 2 agonist
What is step 4 in asthma management?
Increased steroid dose or add leukotriene receptor antagonists or theophylline
What is step 5 in asthma management?
Add daily steroid tablet and refer to specialist
How do you calculate an odds ratio?
(No. with symptoms and exposure/No. with exposure and no symptoms) / (No. with symptoms and no exposure/ No. with no symptoms and no exposure)
What % of couples suffer from infertility?
15%
What bony landmarks is used when administering a pudendal nerve block?
Ischial spine
When does ovulation occur in relation to the next menses?
14 days before
At what stage is embryo transfer performed?
Blastocyst
How many house before ovulation does the LH surge occur?
24-36
How much does HCG increase by in early pregnancy?
Doubles every 48 hours
What is athenospermia?
Low motility
What is teratospermia?
Abnormal forms
What is a major cause of VIN?
HPV 6+11
What is the major risk factor for oesophageal cancer?
Obesity
What happens to the functional residual capacity in pregnancy?
Decreases
What happens to the contractility of the heart in pregnancy?
Increases
What does the mesonephric duct become in males?
Vas deferens
What does the paramesonephric duct in females?
Fornix of the vagina
Name 2 features of fetal alcohol syndrome?
Dysplastic kidneys
Ventricular septal defect
Micrognathia and smooth philtrum
Microencephaly
What is the ichioanal fossa filled with?
Fat
What happens to the volume of drug distribution in pregnancy?
Increases
How do you calculate coverage in a screening programme?
Screened pop/eligible pop x100
What causes the growth of breast ducts in puberty?
Oestrogen
What is the rate of breast cancer?
1 in 8
What is the 1st, 2nd and 3rd line treatment for T2DM?
1 - Metformin
2 - Sulphonylureas or TZD
3 - TZD pr DDP4 or GLP-1
What is the weight effect of metformin?
Causes weight loss
What is the weight effect for sulphonylureas?
May cause wight gain
What is the weight effect for TZD?
May cause weight gain
What is the weight effect for SGLT2 inhibitors?
Causes weight loss
Name 1 sulphonylurea?
Tolbutamide, glipizide, glibenclamide
Name one TZD?
“Glitazones”
Name 1 SGLT2 inhibitors?
Dapagliflozin
Name 1 DDP-4 inhibitor?
Gliptins
Name 1 incretin analogue?
Exenatide
What is the target HbA1C in T2DM?
53mmol/mol
What is the target BP in T2DM?
140/80mmHg or 130/80 if end organ damage
PTH, Ca and Phosphate in primary hyperparathyroidism?
PTH raised
Ca raised
Phosphate decreased
PTH, Ca and Phosphate in secondary hyperparathyroidism?
PTH raised
Ca decreased
Phosphate raised
PTH, Ca, Phosphate in tertiary hyperparathyroidism?
PTH raised
Ca raised
Phosphate decreased
What is the cause of primary hyperparathyroidism?
Solitary adenoma
What is the cause of secondary hyperparathyroidism?
Chronic renal failure
What is the causes of tertiary hyperparathyroidism?
Ongoing hyperplasia following correction of renal disorder
What are the symptoms of primary hyperparathyroidism?
May be asymptomatic
Bones, stones, groans, moans
What is the most common type of thyroid cancer?
Papillary
What is the second more common types of thyroid cancer?
Follicular
Which type of thyroid cancer is associated with hashimotos thyroiditis?
Papillary