Cannabis Flashcards
Which act prohibited cannabis?
Controlled Substances Act of 1970
Cannabinoids are ___ of cannabinoid receptors
a. agonists
b. antagonists
a. agonists
- dronabinol (Marinol) CIII
- nabilone (Cesamet) schedule II
- nabiximols not approved in US
What class is marijuana?
C-I
Hemp may be grown legally as long as it has less than __ % THC
0.3
Agricultural Improvement Act of 2018
Federal Rules:
CBD oil derived from marijuana is considered illegal
a. true
b. false
a. true
CBD oil derived from hemp is legal
hemp removed from controlled substance
___ is a hemp extract with all the cannabinoids except for THC, with means it has all the beneficial properties of cannabis without the high
GENESIS II
Texas rules:
Qualified physicians may prescribe low THC cannabis to a pt with ___
intractable epilepsy
seizure disorder in which the pt’s seizures have been treated by two or more appropriately chosen and maximally titrated antiepileptic drugs that have failed to control the seizures
Texas rules:
Low-THC cannabis has up to __% THC, and at least __% cannabidiol (CBD)
0.5, 10
Colorado rules:
At what age can a pt use marijuana for medical use?
any age
need marijuana registry ID card
Colorado rules:
At what age can someone use marijuana for recreational use?
21 or over
Board of Pharmacy rules set the limits
Medical use is __
a. risk vs risk
b. benefit vs risk
b. benefit vs risk
Recreational use is ___
a. risk vs risk
b. benefit vs risk
a. risk vs risk
Which cannabinoid receptors are in the periphery?
a. CB1
b. CB2
b. CB2
primarily immune related
which cannabinoid receptors are in the nervous system, connective tissues, gonads, glands, and other organs?
a. CB1
b. CB2
a. CB1
Two endocannabinoids that the body naturally produces?
anandamide
2-arachidonoylglycerol
___ = oral THC
dronabinol
What cannabinoid is FDA approved for cachexia in AIDS, CINV, and postoperative n/v?
dronabinol
schedule III
may improve cancer related pain at higher doses
___ is only FDA approved for CINV
a. dronabinol
b. nabilone
c. nabiximols
b. nabilone
___ is not FDA approved
a. dronabinol
b. nabilone
c. nabiximols
c. nabiximols
The majority of supportive data for cannabis and pain relief is for what type of pain?
neuropathic
___ are the plant component responsible for flavors and fragrances of cannabis
terpenes
3 species of cannabis?
sativa
indica
ruderalis
Licensed pharmacist must be on site where marijuana is being sold or dispensed in which state?
a. Connecticut
b New York
c. Minnesota
b. New York
Dispensaries must be owned and operated by pharmacists in which state?
a. Connecticut
b New York
c. Minnesota
a. Connecticut
Law allows up to 8 dispensaries in which state?
a. Connecticut
b New York
c. Minnesota
c. Minnesota
3 are currently running and pharmacists dispense in one
CBD crystals are legal because they contain no THC.
a. true
b. false
b. false
DEA statement: “At present, this material (CBD oil) is being illegally produced and marketed in the United States in violation of two federal laws: The Controlled Substances Act (CSA) and the Federal Food, Drug, and Cosmetic Act (FDCA).”
This would apply to CBD crystals also…
Why is GI use dangerous?
peak concentration is in 1-3 hours
pts do not feel effect and re-dose
CBD inhibits which 3 CYPs?
2C19
3A4
2D6
Cannabis is associated with __ syndrome
amotivational
There is evidence that the same carcinogens in tobacco smoke are present in marijuana smoke.
a. true
b. false
a. true
Takes at least __ hours to resolve impairment from smoking and at least __ hours from oral ingestion
6, 8
What syndrome results from chronic, heavy use of marijuana?
cannabinoid hyperemesis syndrome
Sx are relieved by hot shower
Cannabinoid hyperemesis syndrome is associated with what receptor?
transient receptor potential vanilloid 1 (TRPV1)
What is applied to abdomen, arms, and/or back to treat cannabinoid hyperemesis syndrome?
capsaicin 0.025-0.075%
The synthetic cannabinoid K2 aka spice is a C-I
a. true
b. false
a. true
Use what class of meds to treat synthetic cannabinoid toxicity?
benzos
if agitation/psychosis persists consider antipsychotics (haloperidol)
Synthetic cannabinoid Toxicity:
Rhabdomyolysis is possible so specific focus on __ and ___ monitoring
SCr, potassium
electrolyte monitoring
also perform electrocardiogram
