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7364 Critical Care Block 4 > Cannabis > Flashcards

Cannabis Flashcards

1
Q

Which act prohibited cannabis?

A

Controlled Substances Act of 1970

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2
Q

Cannabinoids are ___ of cannabinoid receptors

a. agonists
b. antagonists

A

a. agonists

  • dronabinol (Marinol) CIII
  • nabilone (Cesamet) schedule II
  • nabiximols not approved in US
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3
Q

What class is marijuana?

A

C-I

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4
Q

Hemp may be grown legally as long as it has less than __ % THC

A

0.3

Agricultural Improvement Act of 2018

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5
Q

Federal Rules:

CBD oil derived from marijuana is considered illegal

a. true
b. false

A

a. true

CBD oil derived from hemp is legal

hemp removed from controlled substance

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6
Q

___ is a hemp extract with all the cannabinoids except for THC, with means it has all the beneficial properties of cannabis without the high

A

GENESIS II

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7
Q

Texas rules:

Qualified physicians may prescribe low THC cannabis to a pt with ___

A

intractable epilepsy

seizure disorder in which the pt’s seizures have been treated by two or more appropriately chosen and maximally titrated antiepileptic drugs that have failed to control the seizures

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8
Q

Texas rules:

Low-THC cannabis has up to __% THC, and at least __% cannabidiol (CBD)

A

0.5, 10

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9
Q

Colorado rules:

At what age can a pt use marijuana for medical use?

A

any age

need marijuana registry ID card

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10
Q

Colorado rules:

At what age can someone use marijuana for recreational use?

A

21 or over

Board of Pharmacy rules set the limits

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11
Q

Medical use is __

a. risk vs risk
b. benefit vs risk

A

b. benefit vs risk

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12
Q

Recreational use is ___

a. risk vs risk
b. benefit vs risk

A

a. risk vs risk

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13
Q

Which cannabinoid receptors are in the periphery?

a. CB1
b. CB2

A

b. CB2

primarily immune related

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14
Q

which cannabinoid receptors are in the nervous system, connective tissues, gonads, glands, and other organs?

a. CB1
b. CB2

A

a. CB1

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15
Q

Two endocannabinoids that the body naturally produces?

A

anandamide

2-arachidonoylglycerol

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16
Q

___ = oral THC

A

dronabinol

17
Q

What cannabinoid is FDA approved for cachexia in AIDS, CINV, and postoperative n/v?

A

dronabinol

schedule III

may improve cancer related pain at higher doses

18
Q

___ is only FDA approved for CINV

a. dronabinol
b. nabilone
c. nabiximols

A

b. nabilone

19
Q

___ is not FDA approved

a. dronabinol
b. nabilone
c. nabiximols

A

c. nabiximols

20
Q

The majority of supportive data for cannabis and pain relief is for what type of pain?

A

neuropathic

21
Q

___ are the plant component responsible for flavors and fragrances of cannabis

A

terpenes

22
Q

3 species of cannabis?

A

sativa
indica
ruderalis

23
Q

Licensed pharmacist must be on site where marijuana is being sold or dispensed in which state?

a. Connecticut
b New York
c. Minnesota

A

b. New York

24
Q

Dispensaries must be owned and operated by pharmacists in which state?

a. Connecticut
b New York
c. Minnesota

A

a. Connecticut

25
Q

Law allows up to 8 dispensaries in which state?

a. Connecticut
b New York
c. Minnesota

A

c. Minnesota

3 are currently running and pharmacists dispense in one

26
Q

CBD crystals are legal because they contain no THC.

a. true
b. false

A

b. false

DEA statement: “At present, this material (CBD oil) is being illegally produced and marketed in the United States in violation of two federal laws: The Controlled Substances Act (CSA) and the Federal Food, Drug, and Cosmetic Act (FDCA).”
This would apply to CBD crystals also…

27
Q

Why is GI use dangerous?

A

peak concentration is in 1-3 hours

pts do not feel effect and re-dose

28
Q

CBD inhibits which 3 CYPs?

A

2C19
3A4
2D6

29
Q

Cannabis is associated with __ syndrome

A

amotivational

30
Q

There is evidence that the same carcinogens in tobacco smoke are present in marijuana smoke.

a. true
b. false

A

a. true

31
Q

Takes at least __ hours to resolve impairment from smoking and at least __ hours from oral ingestion

A

6, 8

32
Q

What syndrome results from chronic, heavy use of marijuana?

A

cannabinoid hyperemesis syndrome

Sx are relieved by hot shower

33
Q

Cannabinoid hyperemesis syndrome is associated with what receptor?

A

transient receptor potential vanilloid 1 (TRPV1)

34
Q

What is applied to abdomen, arms, and/or back to treat cannabinoid hyperemesis syndrome?

A

capsaicin 0.025-0.075%

35
Q

The synthetic cannabinoid K2 aka spice is a C-I

a. true
b. false

A

a. true

36
Q

Use what class of meds to treat synthetic cannabinoid toxicity?

A

benzos

if agitation/psychosis persists consider antipsychotics (haloperidol)

37
Q

Synthetic cannabinoid Toxicity:

Rhabdomyolysis is possible so specific focus on __ and ___ monitoring

A

SCr, potassium

electrolyte monitoring

also perform electrocardiogram

7364 Critical Care Block 4 (4 decks)

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