Cancerul bronhopulmonar Flashcards

1
Q

Cate decese cauzeaza anual Cancerul BP?% de fumatori cu cancer?

A

1,76 milioane pe an; 80%barbati 90%femei

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2
Q

Care sunt subtipurile cancerului BP?

A

Carcinom non-microcelular:-carcinom scuamo-celular ( din cel epiteliale)
-adenocarcinom (din celul glandulare)
-carcinom cu celule mari (slab diferentiat)
Carcinom cu celule mici( din celule neuroendocrine)

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3
Q

Simptome cauzate de efectele tumorale directe/locale?

A
Tusea
Dispnea
Hemoptizia
Durere toracica
weezing
Disfonie
Compresiune nervoasa- tumorile Pancoast ;sdr Horner
Infectii recurente
Invazia nervului frenic
Obstructia venei cave superioare
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4
Q

Simptome cauzate de efectele metastazelor la distanta?

A

Ficat: anorexie,greata, scadere ponderala
Oase; durere si fracturi patologice
Suprarenale: asimptomatic
Creier : meningita carcinomatoasa, cefalee si confuzie
Pleurezii maligne: dispnee si durere pleuritica

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5
Q

Manifestari extrapulmonare non metastatice ale cancerului bronhopulmonar endocrine?

A

Sdr de secretei ectopica de adrenocortiotropina si hormon atidiuretic (SIADH)
Hipercalcemie ( carcinom cu celule scuamoase )
Rar; Hipoglicemie, tirotoxicoza, ginecomastie

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6
Q

Manifestari extrapulmonare non-metastatice ale carcinomului bronsic?

A
Anemie normocitara
Trombocitoza
Hipocratism digital
Osteoartropatie hipertrofica pulmonara
10% din tumorile cu celule mici secreta  hormoni ectopici
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7
Q

Radioterapia cu intentie curativa

A

Alternativa buna la rezectia chirurgicala cu rezultate aproape comparabile.
Electie-cand chirurgia nu e posibila.
10-15% pneumonie post-radioterapie; fibroza pulmonara postiradiere .

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8
Q

Tumorile carcinoide bronsice

A

Rare. Neoplasme cu grad scazut de malignitate si crestere lenta.
Tumori neuroendocrine secretaante de ACTH, fara 5-hidroxitriptamina
Majoritatea asimptomatici, insa pot prezenta obstructii, infectii, hemoptizii.
Tratament de electie-chirurgie

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