cancérogénèse Flashcards

1
Q

initiation

A

une lésion génétique apparait

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2
Q

3 étapes

A

initiation
promotion
progression

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3
Q

promotion

A

une lésion est favorisée par les cytokines, f de croissance, hormones

expansion clonale

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4
Q

progression

A

acquisition des capacités de prolifération ou survie cellulaire
résistance à l’apoptose
dissémination etc

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5
Q

étapes cancer epithélial

A

normal
hyperplasie
dysplasie modérée
dysplasie sévère carcinome in situ
carcinome invasif

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6
Q
A
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