Cancer Treatment Flashcards
(37 cards)
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What is the management and drug of choice for Lung Cancer (NSCLC) - Stage I?
Management: Surgical resection<br></br>Drug of Choice: None<br></br>Alternatives/Notes: None
What is the management and drug of choice for Lung Cancer (NSCLC) - Stage II?
Management: Surgery + adjuvant chemotherapy<br></br>Drug of Choice: Cisplatin + vinorelbine<br></br>Alternatives/Notes: Cisplatin + docetaxel
What is the management and drug of choice for Lung Cancer (NSCLC) - Stage III?
Management: Neoadjuvant chemoradiation<br></br>Drug of Choice: Cisplatin + etoposide<br></br>Alternatives/Notes: Carboplatin-based combinations
What is the management and drug of choice for Lung Cancer (NSCLC) - Stage IV?
Management: Systemic therapy<br></br>Drug of Choice: Cisplatin + pemetrexed (adenocarcinoma)<br></br>Alternatives/Notes: EGFR inhibitors (erlotinib, osimertinib)
What is the management and drug of choice for Breast Cancer - Stage I?
Management: Surgery ± endocrine therapy<br></br>Drug of Choice: Tamoxifen or aromatase inhibitors<br></br>Alternatives/Notes: None
What is the management and drug of choice for Breast Cancer - Stage II?
Management: Surgery + adjuvant chemo/radiation<br></br>Drug of Choice: Doxorubicin + cyclophosphamide + paclitaxel<br></br>Alternatives/Notes: CMF (cyclophosphamide, methotrexate, 5-FU)
What is the management and drug of choice for Breast Cancer - Stage III?
Management: Neoadjuvant chemo + surgery<br></br>Drug of Choice: Trastuzumab + chemo (HER2+)<br></br>Alternatives/Notes: AC-T or taxane-based regimens
What is the management and drug of choice for Breast Cancer - Stage IV?
Management: Systemic therapy<br></br>Drug of Choice: Tamoxifen, CDK4/6 inhibitors<br></br>Alternatives/Notes: Capecitabine, taxanes
What is the management and drug of choice for Liver Cancer (Hepatocellular Carcinoma) - Stage I?
Management: Resection or ablation<br></br>Drug of Choice: None<br></br>Alternatives/Notes: None
What is the management and drug of choice for Liver Cancer (Hepatocellular Carcinoma) - Stage II?
Management: Locoregional therapies<br></br>Drug of Choice: TACE (doxorubicin)<br></br>Alternatives/Notes: Radioembolization
What is the management and drug of choice for Liver Cancer (Hepatocellular Carcinoma) - Stage III?
Management: Systemic therapy<br></br>Drug of Choice: Sorafenib<br></br>Alternatives/Notes: Lenvatinib, regorafenib
What is the management and drug of choice for Liver Cancer (Hepatocellular Carcinoma) - Stage IV?
Management: None<br></br>Drug of Choice: None<br></br>Alternatives/Notes: None
What is the management and drug of choice for Gallbladder Cancer - Stage I?
Management: Simple cholecystectomy<br></br>Drug of Choice: None<br></br>Alternatives/Notes: None
What is the management and drug of choice for Gallbladder Cancer - Stage II?
Management: Extended cholecystectomy<br></br>Drug of Choice: None<br></br>Alternatives/Notes: None
What is the management and drug of choice for Gallbladder Cancer - Stage III?
Management: Radical resection + chemo<br></br>Drug of Choice: Gemcitabine + cisplatin<br></br>Alternatives/Notes: None
What is the management and drug of choice for Gallbladder Cancer - Stage IV?
Management: Palliative chemotherapy<br></br>Drug of Choice: Gemcitabine + cisplatin<br></br>Alternatives/Notes: 5-FU based regimens
What is the management and drug of choice for Esophageal Cancer - Stage I?
Management: Endoscopic resection<br></br>Drug of Choice: None<br></br>Alternatives/Notes: None
What is the management and drug of choice for Esophageal Cancer - Stage II?
Management: Esophagectomy + neoadjuvant chemoradiation<br></br>Drug of Choice: Cisplatin + 5-FU<br></br>Alternatives/Notes: Carboplatin-based regimens
What is the management and drug of choice for Esophageal Cancer - Stage III?
Management: Neoadjuvant chemoradiation + surgery<br></br>Drug of Choice: Cisplatin + 5-FU<br></br>Alternatives/Notes: None
What is the management and drug of choice for Esophageal Cancer - Stage IV?
Management: Palliative chemotherapy<br></br>Drug of Choice: Cisplatin + 5-FU<br></br>Alternatives/Notes: Paclitaxel, ramucirumab
What is the management and drug of choice for Gastric Cancer - Stage I?
Management: Subtotal/total gastrectomy<br></br>Drug of Choice: None<br></br>Alternatives/Notes: None
What is the management and drug of choice for Gastric Cancer - Stage II?
Management: Gastrectomy + adjuvant chemotherapy<br></br>Drug of Choice: 5-FU + leucovorin<br></br>Alternatives/Notes: Capecitabine-based regimens
What is the management and drug of choice for Gastric Cancer - Stage III?
Management: Neoadjuvant chemo + surgery<br></br>Drug of Choice: FLOT (5-FU, oxaliplatin, docetaxel)<br></br>Alternatives/Notes: ECF (epirubicin, cisplatin, 5-FU)
**Drug of Choice:** Capecitabine + oxaliplatin
**Alternatives/Notes:** Taxane-based regimens
**Drug of Choice:** None
**Alternatives/Notes:** None
**Drug of Choice:** 5-FU (high-risk cases)
**Alternatives/Notes:** None
**Drug of Choice:** FOLFOX (5-FU, leucovorin, oxaliplatin)
**Alternatives/Notes:** CAPOX (capecitabine + oxaliplatin)
**Drug of Choice:** FOLFIRI ± targeted agents
**Alternatives/Notes:** Cetuximab (RAS wild-type tumors)
**Drug of Choice:** None
**Alternatives/Notes:** None
**Drug of Choice:** Leuprolide ± bicalutamide
**Alternatives/Notes:** None
**Drug of Choice:** Leuprolide ± bicalutamide
**Alternatives/Notes:** None
**Drug of Choice:** Leuprolide (castration-sensitive), Docetaxel (castration-resistant)
**Alternatives/Notes:** Abiraterone, enzalutamide
**Drug of Choice:** Etoposide + cisplatin (with concurrent radiation)
**Alternatives/Notes:** Carboplatin may be used instead of cisplatin
**Drug of Choice:** None
**Alternatives/Notes:** For patients with good performance status
**Drug of Choice:** Atezolizumab + carboplatin + etoposide
**Alternatives/Notes:** Durvalumab is an alternative to atezolizumab
**Drug of Choice:** None
**Alternatives/Notes:** Focus on symptom management and best supportive care
