Cancer Therapy Flashcards
0
Q
Immunotherapy:
•trastuzumab (herceptin)
A
Used to stop the growth of breast tumors that express HER2 neuro receptor.
It’s a monoclonal antibody that binds the the receptor.
1
Q
Tamoxifen (Nolvadex)
A
PO med that interferes with estrogen activity.
Estrogen antagonist
2
Q
Letrozole
A
aromatose inhibitor
Prevents aromatose from producing estrogen by competitive reversible binding.
3
Q
Colorectal chemo.
IV fluorouracil:
A
Pyrimidine analog that belongs to family of drugs called antimetabolites
Blocks synthesis of pyrimidine thymidine a nucleoside required for DNA replication.
4
Q
Colorectal cancer:
•Folinic acid (leucovorin)
A
A derivative of tetrahydrofolic acid used with methotrexate to rescue bone marrow as GI mucosal cells.
