Cancer terms Flashcards

1
Q

define hyperplasia

A

increase in cell number due to a stimulus

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2
Q

what are some examples of hyperplasia

A
  • oestrogen causing build up of uterus wall
  • lymph nodes
  • breast tissue in puberty
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3
Q

define hypertrophy

A

increase in cell size due to stimulus

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4
Q

what are some examples of hypertrophy

A
  • Left ventricular hypertrophy eg from aortic stenosis or hypertension
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5
Q

what is HOCM

A

hypertrophic obstructive cardiomyopathy

- caused by hypertrophy

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6
Q

define atrophy

A

decrease in cell size/ and or number

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7
Q

what causes atrophy

A

occurs due to withdrawal of stimulus

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8
Q

what are some examples of atrophy

A
  • bed bound muscle wastage

- getting a cast off and having muscle wastage

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9
Q

define metaplasia

A

REVERSIBLE change from one mature cell type to another mature cell type

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10
Q

what is an example of metaplasia

A

Barrett’s oesophagus

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11
Q

define neoplasia

A

new cell growth without stimulus

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12
Q

is neoplasia malignant or benign

A

either

- warts are benign

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13
Q

define dysplasia

A

disordered growth

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14
Q

define malignant

A

has capacity to spread

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15
Q

what is a ‘signet ring’ in terms of cancer

A

when cytoplasm pushes the nucleus to the edge of cell

- BAD NEWS

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16
Q

what type of asbestos is related to mesothelioma

A

Crocidolite

17
Q

what is the cause of Lynch syndrome

A

mutation in mismatch repair genes (MMR genes)

18
Q

What is Lynch syndrome

A

Hereditary syndrome which is NON-POLYPOSIS COLORECTAL CANCER