Cancer Proteins and their tumor Flashcards
1
Q
MiR-200
A
Genera metastasis
2
Q
MiR-155
A
B cell lymphoma(block MYC)
3
Q
MiR-15,16
A
Chronic Lymphoid leukemia
BCL-2
4
Q
HPV
Strains…
Viral protein
Host protein
Cancer
A
16,18
E6,E7
p53, RB
Cervical, oropharyngeal
5
Q
BCL-2
A
Follicular lymphoma(B cell)
6
Q
ERB1
Cancer
Protein
A
Lung adenocarcinoma
EGFR
7
Q
ERB2
Cancer
Protein
A
Breast cancer
HER2
8
Q
EML4-ALK
A
Lung adenocarcinoma
9
Q
RAS
A
CARCINOMA
Pancreas, gall bladder, colon, lung, endometrial, thyroid, myeloid leukemia
10
Q
BRAF
A
Hairy cell leukemia, melanoma, benign nevi(Moles)
11
Q
SHH
A
Holoprosenceohaly, basal cell carcinoma
Brain, lung, prostate, mammary
12
Q
MYC
A
Burkett Lymphoma, neuroblastoma, CARCINOMAS
13
Q
APC
A
Colon cancer,
14
Q
VHL
A
carcinoma
Retina, cerebellum, kidney
15
Q
RB
A
Retinoblastoma, osteosarcoma, glioblastoma, small cell carcinoma lung, breast, bladder, oropharyngeal(E7)
