Cancer Pathogenesis (Liver and Lung) Flashcards

1
Q

What does HCC stand for?

A

Hepatocellular carcinoma

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2
Q

What are the main risk factors for liver cancer?

A

HBV, HCV infection
Alcohol consumption
Aflatoxin exposure
Non-alcoholic fatty liver disease (NAFLD)

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3
Q

What are the 3 mechanisms by which HBV is involved in HCC?

A

Chromosomal instability
Integration of its genome
Modulation of cell proliferation

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