Cancer Pathogenesis (Liver and Lung) Flashcards
1
Q
What does HCC stand for?
A
Hepatocellular carcinoma
2
Q
What are the main risk factors for liver cancer?
A
HBV, HCV infection
Alcohol consumption
Aflatoxin exposure
Non-alcoholic fatty liver disease (NAFLD)
3
Q
What are the 3 mechanisms by which HBV is involved in HCC?
A
Chromosomal instability
Integration of its genome
Modulation of cell proliferation