Cancer medications

Question 1

List 2 examples of biological and targeted therapies

Answer 1

Trastuzumab
Imatinib

Question 2

What type of cancer is Trastuzumab used for?

Answer 2

Breast cancer

Question 3

what is the primary action of Trastumuzab

Answer 3

Targets those breast cancer cells that have over expression of the HER protein

Question 4

Expected side effects of Trastuzumab

Answer 4

• Nausea
• Vomiting
• Mild flu like symptoms

Question 5

Nursing concerns with Trastuzumab

Answer 5

Monitor for
* hypersensitivity reaction
* Cardio toxicity
* Tachycardia
* Dyspnea
* Edema
* Fluid status

Question 6

Patient education for Trastuzumab

Answer 6

Report SOB, chest pain, edema

Question 7

What type of cancer is Imatinib used for

Answer 7

Chronic Myeloid Leukemia (CML) Leukemia

Question 8

What is the main action of Imatinib?

Answer 8

Tyrosine Kinase Inhibitor

Question 9

Expected side effects of Imatinib

Answer 9

• GI discomfort
• Nausea and Vomiting
• Flu like symptoms

Question 10

Nursing concerns with Imatinib

Answer 10

Give with food
Monitor:
* vitamin K levels
* Edema
* CBC for neutropenia

Question 11

Patient education for Imatinib

Answer 11

Hygeine to prevent infection

Question 12

which three medications are used to increase blood production in all cancers?

Answer 12

Filgrastim
Erythropoietin
Oprelvekin

Question 13

what is the action of filgrastim

Answer 13

stimulates neutrophil production

Question 14

what are the side effects of filgrastim

Answer 14

Bone pain

Question 15

What are the nursing considerations for Filgrastim?

Answer 15

Monitor CBC
Give tylenol for bone pain

Question 16

What is the action of Erythropoietin?

Answer 16

Increases production of RBC

Question 17

What are the side effects of Erythropoietin?

Answer 17

Increased BP
Body aches

Question 18

What are the nursing actions for Erythropoietin?

Answer 18

Monitor
* HBG
* Headaches
* Hypertension
* Thrombotic events

Question 19

What is the main action of Oprelvekin?

Answer 19

Increases platelet production

Question 20

What are the side effects of Oprelvekin?

Answer 20

May increase fluid retention
Can cause dysryhthmia in CHF patients

Question 21

What are the nursig actions for Oprelvekin?

Answer 21

Monitor
* CBC
* Platelet
* Electrolytes
* I&O

Question 22

What are the two hormone therapies ?

Answer 22

Leuprolide
Tamoxifen

Question 23

What type of cancer is Leuprolide used for?

Answer 23

Prostate Cancer

Question 24

What is the main action of Leuprolide?

Answer 24

Gonadotropine releasing Hormone
Stops the testes from producing testosterone

Question 25

what are the expected side effects of Leuprolide?

Answer 25

Hot flashes Decreased libido gynecomastia

Question 26

What are the nursing concerns with Leuprolide?

Answer 26

Monitor for dysrhthmia assess pulmonary edema monitor for risk of DVT/Clot

Question 27

What is the patient education for Leuprolide?

Answer 27

Increase Calcium and Vit D in diet Exercise to increase bone density Monitor PSA

Question 28

What is the main action of Tamoxifen?

Answer 28

Estrogen receptor Blocker Stops cancer getting the estrogen it needs to grow

Question 29

What are the expected side effects of Tamoxifen?

Answer 29

Nausea and vomiting PE hot flashes

Question 30

what is the patient teaching for Tamoxifen?

Answer 30

Monitor for abnormal bleeding Monitor Calcium levels Signs and symptoms of retinopathy and cataracts Given for 5 years

Question 31

What class of medication is ondansetron?

Answer 31

Anti-emetic

Question 32

What is the main action of ondansetron?

Answer 32

Prevents emesis by blocking receptors at the CTZ

Question 33

what are the expected side effects of ondansetron

Answer 33

Headache, Dizziness, Diarrhea

Question 34

Nursing considerations with ondansetron

Answer 34

Monitor ECG in patients with cardiac disorders (may cause long QT intervals)

Question 35

Patient teaching with ondansetron

Answer 35

Take 1 hr before Chemo use 3x daily orally for radiation patients