Cancer medications Flashcards

1
Q

List 2 examples of biological and targeted therapies

A

Trastuzumab
Imatinib

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2
Q

What type of cancer is Trastuzumab used for?

A

Breast cancer

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3
Q

what is the primary action of Trastumuzab

A

Targets those breast cancer cells that have over expression of the HER protein

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4
Q

Expected side effects of Trastuzumab

A
  • Nausea
  • Vomiting
  • Mild flu like symptoms
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5
Q

Nursing concerns with Trastuzumab

A

Monitor for
* hypersensitivity reaction
* Cardio toxicity
* Tachycardia
* Dyspnea
* Edema
* Fluid status

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6
Q

Patient education for Trastuzumab

A

Report SOB, chest pain, edema

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7
Q

What type of cancer is Imatinib used for

A

Chronic Myeloid Leukemia (CML) Leukemia

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8
Q

What is the main action of Imatinib?

A

Tyrosine Kinase Inhibitor

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9
Q

Expected side effects of Imatinib

A
  • GI discomfort
  • Nausea and Vomiting
  • Flu like symptoms
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10
Q

Nursing concerns with Imatinib

A

Give with food
Monitor:
* vitamin K levels
* Edema
* CBC for neutropenia

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11
Q

Patient education for Imatinib

A

Hygeine to prevent infection

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12
Q

which three medications are used to increase blood production in all cancers?

A

Filgrastim
Erythropoietin
Oprelvekin

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13
Q

what is the action of filgrastim

A

stimulates neutrophil production

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14
Q

what are the side effects of filgrastim

A

Bone pain

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15
Q

What are the nursing considerations for Filgrastim?

A

Monitor CBC
Give tylenol for bone pain

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16
Q

What is the action of Erythropoietin?

A

Increases production of RBC

17
Q

What are the side effects of Erythropoietin?

A

Increased BP
Body aches

18
Q

What are the nursing actions for Erythropoietin?

A

Monitor
* HBG
* Headaches
* Hypertension
* Thrombotic events

19
Q

What is the main action of Oprelvekin?

A

Increases platelet production

20
Q

What are the side effects of Oprelvekin?

A

May increase fluid retention
Can cause dysryhthmia in CHF patients

21
Q

What are the nursig actions for Oprelvekin?

A

Monitor
* CBC
* Platelet
* Electrolytes
* I&O

22
Q

What are the two hormone therapies ?

A

Leuprolide
Tamoxifen

23
Q

What type of cancer is Leuprolide used for?

A

Prostate Cancer

24
Q

What is the main action of Leuprolide?

A

Gonadotropine releasing Hormone
Stops the testes from producing testosterone

25
Q

what are the expected side effects of Leuprolide?

A

Hot flashes
Decreased libido
gynecomastia

26
Q

What are the nursing concerns with Leuprolide?

A

Monitor for dysrhthmia
assess pulmonary edema
monitor for risk of DVT/Clot

27
Q

What is the patient education for Leuprolide?

A

Increase Calcium and Vit D in diet
Exercise to increase bone density
Monitor PSA

28
Q

What is the main action of Tamoxifen?

A

Estrogen receptor Blocker
Stops cancer getting the estrogen it needs to grow

29
Q

What are the expected side effects of Tamoxifen?

A

Nausea and vomiting
PE
hot flashes

30
Q

what is the patient teaching for Tamoxifen?

A

Monitor for abnormal bleeding
Monitor Calcium levels
Signs and symptoms of retinopathy and cataracts
Given for 5 years

31
Q

What class of medication is ondansetron?

A

Anti-emetic

32
Q

What is the main action of ondansetron?

A

Prevents emesis by blocking receptors at the CTZ

33
Q

what are the expected side effects of ondansetron

A

Headache, Dizziness, Diarrhea

34
Q

Nursing considerations with ondansetron

A

Monitor ECG in patients with cardiac disorders (may cause long QT intervals)

35
Q

Patient teaching with ondansetron

A

Take 1 hr before Chemo
use 3x daily orally for radiation patients