câncer colo uterino Flashcards

1
Q

epidemio

A

segundo tipo de câncer mais comum entre as mulheres

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2
Q

tipos histológicos

A

carcinoma de céls escamosas**

adenocarcinoma

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3
Q

HPV

A

alto risco: 16 e 18

tropismo por céls basais imaturas do ep escamoso da junção escamocolunar

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4
Q

proteína E6

A

inativa p53

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5
Q

proteina E7

A

inativa pRB

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6
Q

malignidade

A

vírus antes na forma epissomal passa para linear e se incorpora com o DNA

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7
Q

NIC I

A

• alterações displásicas no terço inferior do epitélio escamoso

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8
Q

NIC II

A
  • displasia no terço médio do epitélio

* Presença de mitoses acima da camada basal.

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9
Q

NIC III

A
  • Não apresentam coilocitose.

* mitoses anormais em todas as camadas

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10
Q

estágio I

A

tumores confinados no colo uterino

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11
Q

estágio 2

A

vagina superior e órgaos paracervicais

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12
Q

estágio 3

A
  • vagina inferior
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13
Q

estágio 4

A

bexiga, reto

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14
Q

gardasil

A

tetravalente

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15
Q

cervarix

A

bivalente

não protege contra as verrugas genitais

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