Cancer Chemotherapy Quiz Flashcards
The following are combination of penicillin and beta lactamase inhibitors:
I. Amoxicillin + clavulanic acid
II. Ampicillin + sulbactam
III. Piperacillin+tazobactam
IV. Ceftazidime + avibactam
l, ll, lll only
The following are true about antibiotics:
1. Antibiotics can be used as preventive or therapeutically used for the treatment of secondary infection that may occur with viral disease.
II. Taking medication prescribed for another patient without obtaining medical case is another frequent misuse or abuse.
III. Antibiotics should be taken for the full prescribed course to ensure the suppression and destruction of all pathogens.
IV. Disappearance of the symptoms is an indication that infection has been adequately treated and medication can now be discontinued.
l ,ll, lll only
Pen G is administered through injection:
Pen G is not stable in gastric acid.
Its action is specific for staphylococcal infection.
Dosage is 500mg po)
It has a broad spectrum of activity
Pen G is not stable in gastric acid.
Lactam and thiozolidine:
Cephalosporins
Penicillins
Monobactams
Carbapenems
Penicillins
True or False:
Patients who are allergic to penicillin should be considered allergic to all penicillins
True
The first true antibiotics derived from a number of strains of common molds found in bread and fruit.
Cephalosporins
Penicillins
Polymyxin
Vancomycin
Penicillins
The following statements are true except:
Bacteriostatic agents cause the body fluids that are not isotonic to result in killing of bacteria.
Bactericidal agents can cause lysis of the cell by weakening the cell wall.
Bacteriostatic agents inhibit the synthesis of metabolites essential to bacteria.
Bacteriostatic static agents either causes death of the bacterial cell or
destruction of the cell.
?
The first penicillin developed and the drug of choice for treating many infections such as gonorrhoea and streptococcal infections:
Pen V
Methicillin
Amoxicillin
Pen G
Pen G
True or False:
Antibiotics are ineffective for the treatment of viral infections, but can be used with viral diseases when secondary infection are present.
True
True or False:
Altering the permeability of the cell membrane which results in leakage of essential metabolic substances of bacteria is the mechanism of action of bactericidal agent.
True
Bacterial cell wall:
I. It contains greater than or 10 layers of peptidoglycans in g(+) bacteria.
II. Beta lactam interrupts the terminal transpeptidation process within the bacterial cell wall.
III. Peptidoglycans are polysaccharides which contains sugar and amino acids that provides mechanical stability to bacterial cell
wall.
IV. Peptidoglycans maintains cell shape.
I only
Il & III only
I, ll, lll only
I, II, III, IV
I, II, III, IV
A highly nephrotoxic drug when used orally, obtained from the strain of Bacillus subtilis and used for the treatment of infections due to mixed bacterial flora in surface lesions of the skin or mucous membrane:
Bacitracin
Daptomycin
Fosfomycin
Telavancin
Bacitracin
This drug is the only available in their class, and are more resistant to hydrolysis by chromosomal beta lactamases:
Cefepime
Cefamandole
Cefixime
Cefdinir
Cefepime
The only first generation parenteral preparations which is still in general use:
Cefazolin
Cefonicid
Cefotaxime
Cifixime
Cefazolin
Combinations of this drug are used for the treatment of meningitis:
Ceftolozane-Tazobactam
Ceftazidime Avimactan
Ceftriaxone - Cefotaxime
Cefamandole- Cefuroxime
Ceftriaxone - Cefotaxime
Drug of choice for endocarditis caused by MRSA:
Teicoplanin
Vancomycin
Daptomycin
Fosfomycin
Vancomycin
An antibiotic produced by Streptomyces orchidaceous and the 2nd drug of choice for the treatment of tuberculosis:
Bcitracin
Cycloserine
Fosfomycin
Teicoplanin
Cycloserine
These drugs have expanded g(-) bacteria and can cross the blood brain barrier:
1st generation cephalosporins
2nd generation cephalosporins
3rd generation cephalosporins
4th generation cephalosporins
3rd generation cephalosporins
A novel cyclic lipopeptide fermentation product of S. roseosporus and an effective alternative for Vancomycin:
Fosfomycin
Teicoolanin
Daptomycin
Telavancin
Daptomycin
Caution need to be exercised when prescribing a cephalosporin to a patient with which known allergy:
Peanuts
Seafoods
Chicken
Penicillin
Penicillin
The process by which the drug slides between DNA base pairs & inhibits DNA synthesis:
DNA synthesis
Transpeptidation
Alkylation
Intercalation
Intercalation
The following agents works through by affecting the microtubule, except:
Docetaxel
Vinblastine
Vincristine
Vinorelbine
Docetaxel
Common side effects of patient receiving chemotherapy:
I. Hair loss
II. Nausea
III. Vomiting
IV. Diarrhea
I, ll, lll, lV
Which of the following combination is the treatment of choice for stage III & stage IV ovarian cancer:
Paclitaxel & cisplatin
Carboplatin & paclitaxel
Cisplatin & nivolumab
Dacarbazine & Temozolomide
Carboplatin & paclitaxel
