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Pharmacology II > Arrhythmias & Coagulation > Flashcards

Arrhythmias & Coagulation Flashcards

1
Q

It shows phase 3 of the action potential-ventricular repolarization:

A

T wave

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2
Q

The following antiarrhythmic drugs slows the heart rate except:
I. Procainamide
II. Quinidine
III. Flecainide
IV. Propafenone

A

“I.2.3.4”

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3
Q

The appropriate route of administration for lidocaine

A

IV

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4
Q

This may occur when the electrical conduction pathways malfunctions

A

Arrhythmias

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5
Q

This phase is also called rapid depolarization wherein sodium ions enter the cell through fast channels

A

Phase 0

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6
Q

Specialized myocardial structure that initiates electrical impulses to stimulate contraction

A

SA Node

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7
Q

It describes the Class 1 anti-arrhythmics drugs

A

Sodium channel blockade

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8
Q

Agent of choice for determination of ventricular tachycardia and prevention of ventricular fibrillation after cardioversion

A

Lidocaine

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9
Q

The drug of choice for prompt conversion of paroxysmal SVT to sinus rhythm due to its high efficacy and very short duration of action

A

Adenosine

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10
Q

An anti-arrhythmic drug which is a calcium channel blocker is classified as

A

Class 4

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11
Q

A brand name of amiodarone

A

Cordarone

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12
Q

Drug that prolongs effective refractory period by prolonging the action potential.

A

Verapamil

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13
Q

Which of the following is important to monitor in patients receiving anti-arrhythmic drugs?

A

Electrolytes

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14
Q

antiarrhythmic drug that is associated with an adverse effect of cinchonism?

A

Quinidine

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15
Q

An example of class 2 anti-arrhythmic drugs

A

Propranolol

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16
Q

A clotting enzyme

A

Thrombin

17
Q

A clot that floats in the blood or moves through the circulatory system

A

Embolus

18
Q

A blood glycoprotein involved on hemostasis especially in platelet adhesion

A

Von Willebrand factor

19
Q

T or F
Heparin has an immediate onset but short duration of action and can cross the placenta

A

False

20
Q

How are low-molecular-weight heparins usually administered?

A

Subcutaneously

21
Q

Arrhythmia, thrombocytopenia, varicose vein, are prone to thrombus formation

A

N/A

22
Q

What is the purpose of International Normalized Ratio (INR) monitoring

A

To monitor warfarin therapy

23
Q

The mechanism of action of the anticoagulant effect of warfarin derivative involves

A

An action that blocks the release of y-carboxylation of several glutamate residues in prothrombin.

24
Q

A bivalent inhibitor of thrombin which is also used to inhibit platelet activation and useful in percutaneous coronary angioplasty

A

Bivalirudin

25
Q

A replacement source for Hemophilia A

A

Recombinant factor Vlll products

26
Q

An antidote for warfarin toxicity

A

Vitamin K

27
Q

Streptokinase is used to:

A

Dissolve clot

28
Q

The main initiator in of blood coagulation in vivo

A

Tissue Factor Vlla

29
Q

The antidote for heparin overdose

A

Protamine sulfate

30
Q

An antiplatelet drug

A

Dipyridamole

Pharmacology II (8 decks)

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