Cancer Chemotherapeutics Flashcards
ALL
Vincristine + prednisone + other agent (6-MP, Cyclophosphamide, Danorubicin)
ALL (prophylaxis of CNS leukemia)
Methotrexate (intrathecal)
CML (first line)
Imantinib, Dasatanib, nilotinib
AML
Cytarabine (+ Idarubicin in induction)
CML (2nd line)
Busulfan
CLL
COP: Cyclophosphamide, Vincristine, Prednisone
CHOP: Cyclophosphamide, Vincristine, Prednisone, Doxorubicin
Hodgkins I&II
ABVD: Doxorubicin, Bleomycin, Vinblastine, Dacarbazine
Hodgkin III/IV
ABVD: Doxorubicin, Bleomycin, Vinblastine, Dacarbazine (more effective, less toxic)
MOPP: Mechlorethamine, Vincristine, Procarbazine, Prednisone
Stanford V: Doxorubicin, Bleomycin, Vinblastine, Mechlorethamine, Vincristine, Etoposide, Prednisone
Non-Hodgkin (palliative)
CHOP: Cyclophosphamide, Vincristine, Prednisone, Doxorubicin
R-CHOP: add Rituximab
Multiple Myeloma
MP Protocol: Melphalan, Prednisone
VAD: Vincristine, Doxorubicin, Dexamethasone
Breast Cancer (Stage I/II)(1-3LN)
CMF: Cyclophosphamide, methotrexate, 5-FU
FAC: 5-FU, Doxorubicin, Cyclophosphamide
Breast Cancer (Stage I/II) (4+LN) (Her2)
Trastuzumab
Breast Cancer (Stage III/IV) (Her2)
1) Trastuzumab, Docetaxel, pertuzumab
2) lapatinib,
3) Anthracyclines (rubicins)
4) Taxanes
Colorectal (high risk post surgical)
FOLFOX: Leucovorin, 5-FU, Oxaliplatin
XELOX: Capecitabine, Oxaliplatin
Colorectal Cancer (metastatic)
FOLFIRI: Leucovorin, 5-FU, Irinotecan