Cancer Chemotherapeutics Flashcards

1
Q

ALL

A

Vincristine + prednisone + other agent (6-MP, Cyclophosphamide, Danorubicin)

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2
Q

ALL (prophylaxis of CNS leukemia)

A

Methotrexate (intrathecal)

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3
Q

CML (first line)

A

Imantinib, Dasatanib, nilotinib

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4
Q

AML

A

Cytarabine (+ Idarubicin in induction)

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5
Q

CML (2nd line)

A

Busulfan

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6
Q

CLL

A

COP: Cyclophosphamide, Vincristine, Prednisone
CHOP: Cyclophosphamide, Vincristine, Prednisone, Doxorubicin

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7
Q

Hodgkins I&II

A

ABVD: Doxorubicin, Bleomycin, Vinblastine, Dacarbazine

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8
Q

Hodgkin III/IV

A

ABVD: Doxorubicin, Bleomycin, Vinblastine, Dacarbazine (more effective, less toxic)
MOPP: Mechlorethamine, Vincristine, Procarbazine, Prednisone
Stanford V: Doxorubicin, Bleomycin, Vinblastine, Mechlorethamine, Vincristine, Etoposide, Prednisone

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9
Q

Non-Hodgkin (palliative)

A

CHOP: Cyclophosphamide, Vincristine, Prednisone, Doxorubicin

R-CHOP: add Rituximab

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10
Q

Multiple Myeloma

A

MP Protocol: Melphalan, Prednisone

VAD: Vincristine, Doxorubicin, Dexamethasone

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11
Q

Breast Cancer (Stage I/II)(1-3LN)

A

CMF: Cyclophosphamide, methotrexate, 5-FU
FAC: 5-FU, Doxorubicin, Cyclophosphamide

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12
Q

Breast Cancer (Stage I/II) (4+LN) (Her2)

A

Trastuzumab

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13
Q

Breast Cancer (Stage III/IV) (Her2)

A

1) Trastuzumab, Docetaxel, pertuzumab
2) lapatinib,
3) Anthracyclines (rubicins)
4) Taxanes

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14
Q

Colorectal (high risk post surgical)

A

FOLFOX: Leucovorin, 5-FU, Oxaliplatin
XELOX: Capecitabine, Oxaliplatin

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15
Q

Colorectal Cancer (metastatic)

A

FOLFIRI: Leucovorin, 5-FU, Irinotecan

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16
Q

Pancreatic Cancer (metastatic)

A

FOLFIRINOX

17
Q

NSCLC

A

Platinum agent + second drug

18
Q

Testicular Cancer

A

PEB: Cisplatin, Etoposide, Bleomycin

19
Q

Brain Cancer

A

PCV: Procarbazine, Lomustine, Vincristine

20
Q

Glioblastoma

A

Bevacizumab