Cancer Flashcards

1
Q

oncogene

A

at least one activated mutation

mutated or over-expressed gene that induces uncontrolled cell growth by promoting cell cycle progression or inhibition of apoptosis

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2
Q

tumor suppressor gene

A

regulates DNA repair by repressing or pausing the cell cycle to ensure only normal cells proceed to the division stage and induce programmed cell death if repair fails

requires 2 activated mutations

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