Cancer Flashcards
1
Q
oncogene
A
at least one activated mutation
mutated or over-expressed gene that induces uncontrolled cell growth by promoting cell cycle progression or inhibition of apoptosis
2
Q
tumor suppressor gene
A
regulates DNA repair by repressing or pausing the cell cycle to ensure only normal cells proceed to the division stage and induce programmed cell death if repair fails
requires 2 activated mutations