Cancer Flashcards
Osteosarcoma location
MC in femur, tibia, humerus
90% in metaphysis
Osteosarcoma Onset
2nd decade of life
Osteosarcoma RF
Rapid bone growth
History of retinoblastoma
Ionizing radiation exposure
Genetic RF
Osteosarcoma Clinical features
Pain and swelling
Mass 40% of time
Dec ROM
Possible pathologic fx
Ewing Sarcoma Onset
5-25 yo
MC teenage boys
Ewing Sarcoma RF
Rapid bone growth
Caucasian race
Ewing Sarcoma Clinical Features
Pain and swelling
Mass always present initially
Dec ROM
Possible pathologic fx
MC solid tumor in children
Brain tumors
MC location of brain tumors
2/3’s infraentorial
MC types of brain tumors in children
Astrocytoma
Ependymomas
Medulloblastoma
MC brain tumor in children
20% Medulloblastoma
MC in cerebellum
Ependymoma characteristics
Generate w/in ventricles
Can be aggressive
MC differentiated and benign
Tx w/ surgery
Brain stem Glioma characteristics
Fast or slow growing
Not resectable, require chemo or radiation
Glioblastoma muliforme high grade gliomas and poor prognosis
Pilocytic astrocytoma characteristics
MC low grade glioma
Cytic an tx w/resection
Gangliogliomas characteristics
low grade glioma
slow growing and benign
Craniopharyngioma characteristics
Congetital tumors
Typically benign
Hydrocephalus and endocrine sx common
93% growth failure
Pineal tumor characteristics
Posterior portion of 3rd ventricle
Most often germinomas
Osteoid Osteoma
Benign solitary tumor of bone characterized by nocturnal pain that is relieved with NSAIDs
Osteoid Osteoma CF
Initially localized bone pain Acute or subacute Pain worse at night and activity Dramatically relieved by NSAIDs Constitutional sx absent
