Cancer Flashcards

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0
Q

Why are proliferation genes also known as proto-oncogenes?

A

When they mutate they form oncogenes which are found in many cancers.

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1
Q

What are proliferation genes?

A

Genes that code for proteins which promote cell division only when an external signal is received.

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2
Q

What happens when proliferation genes mutate?

A

Give proteins with abnormal shapes which stimulate EXCESSIVE CELL DIVISION and TUMOUR FORMATION even in the absence of any external signal.

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3
Q

Are oncogenes dominant or recessive alleles?

A

Dominant

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4
Q

What do anti proliferation genes do?

A

Code for proteins which restrict cell division by operating at the cell cycle checkpoints

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5
Q

In which type of genes are mutations recessive?

A

Antiproliferation genes

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6
Q

What is an oncogene?

A

Cancer causing gene; mutated proliferation gene

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