Cancer Flashcards
Why are proliferation genes also known as proto-oncogenes?
When they mutate they form oncogenes which are found in many cancers.
What are proliferation genes?
Genes that code for proteins which promote cell division only when an external signal is received.
What happens when proliferation genes mutate?
Give proteins with abnormal shapes which stimulate EXCESSIVE CELL DIVISION and TUMOUR FORMATION even in the absence of any external signal.
Are oncogenes dominant or recessive alleles?
Dominant
What do anti proliferation genes do?
Code for proteins which restrict cell division by operating at the cell cycle checkpoints
In which type of genes are mutations recessive?
Antiproliferation genes
What is an oncogene?
Cancer causing gene; mutated proliferation gene