Cancer Flashcards

1
Q

What is another name for a tumor

A

Neoplasm

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2
Q

What is a harmful byproduct of a benign tumor

A

A mass effect (crushes near structures

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3
Q

How do malignant tumors travel

A

Tumor sheds cells that get carried by circulatory system and grow in distant sites

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4
Q

How do malignant cells look under a microscope

A

Disorganized and undifferentiated

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5
Q

Malignant cells grow rapid. How do they maintain nutrients

A

Create their own small vessels

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6
Q

What is associated with a malignant tumor

A

Necrosis, ulceration, cavity formation

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7
Q

Where does carcinoma arise from

A

Epithelial tissue

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8
Q

What tissue does adenocarcinomas arise from

A

Glandular

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9
Q

What tissue does sarcoma arise from

A

Connective tissue

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10
Q

What is another name for lung cancer

A

Bronchogenic carcinoma

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11
Q

What tissue is impacted by lung cancer

A

Epithelialium

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12
Q

What are non-small cell carcinomas

A

Squamous cell carcinoma

Adenocarcinoma

Large cell carcinoma

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13
Q

Types of small cell lung carcinoma

A

Oat cell cancer

Combined or mixed small cell carcinoma

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14
Q

What percent of lung cancer is SCLC

A

10-15%

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15
Q

What is the strongest correlation to development of SCLC

A

Smoking

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16
Q

How does SCLC tumors grow

A

Fast
Large
Spread early

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17
Q

Survive of SCLC w/o treatment

A

1-3 months

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18
Q

What percent of people with SCLC respond to treatment

A

90%

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19
Q

Within what time do patients w/ SCLC relapse

A

24months

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20
Q

What percent of lung cancer is squamous cell carcinoma

A

25-30%

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21
Q

How does squamous cell carcinoma grow

A

Slow
Spreads late
Arises in central bronchus or hilum

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22
Q

What percent of lung cancer is adenocarcinoma

A

40%

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23
Q

How do adenocarcinoma tumors grow

A

Moderate
Spread Early
Situated in peripheral lung

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24
Q

What percent of lung cancer is LCC

A

10-15%

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25
Is large cell carcinoma differentiated
No
26
How do large cell carcinoma tumors grow
Fast Early to distant location Situated in periphery and central lung
27
Complication with large cell carcinoma
CW pain, pleural effusion, pneumonia, hemoptysis, and pulmonary cavities
28
Most frequent cancers in the U.S.
Breast Prostate Lung
29
What is the 5 year lung cancer survival percentage
15%
30
How many new cases of lung cancer is there annually
234,580
31
How many people die from lung cancer a year
125,070
32
What is the average age for lung cancer diagnosis
70 years old
33
What percent more likely is black men to get lung cancer than white men
12%
34
What percent more likely are white women to have lung cancer than black women
16%
35
How many people alive today have been diagnosed with lung cancer
380,000
36
How does a transbronchial biopsy work
A bronchoscope is positioned Forceps are extended beyond view of bronchoscope (visible on fluoroscope) Physician bites a sample with forceps Physician pulls forceps out of scope
37
Calculation for pack day
How many packs a day/days for year
38
What is the risk of menthol
Increased because it encourages deeper breaths
39
What is the risk of cigars
Almost as high as cigarettes
40
Difference between a nodule and a mass
A mass is greater than 3cm
41
What causes pancoast syndrome
A tumor near the apex compresses the nerves and vessels of brachial plexus
42
What are the effects of pancoast syndrome
Drooping of one eyelid (ptosis) Small pupils Reduced or absent perspiration on the same side of the face.
43
What causes superior vena cava syndrome
A tumor near upper portion of right lung obstructs blood flow at the SVC
44
What does SVC syndrome do
Vessels of face, neck, arms, upper chest swell with blood causing swelling
45
Explain paraneoplastic syndrome
Distant effects on the body due to changes to the bodies metabolism brought on by the tumor
46
Metabolic effects caused by paraneoplastic syndrome
Hypercalcemia Excess growth of bones (fingertips) Blood clots
47
Primary goal of diagnostic procedures (cancer)
Confirm the presence of lung carcinoma Establish the cancer cell type confirm Confirm stage of cancer
48
Ways to search for a tumor
CXR CT PET MRI Bone scan
49
Role of a CT in cancer diagnoses
Shape and size of the lesion
50
Use of a PET scan in a cancer diagnosis
Identify “hot spot” glucose uptake
51
What does TNM stand for
TUMOR How big? Spreading? NODE Metastasis Tumor close or far METASTASIS How distant How many How much
52
Describe the TNM “staging” system for lung cancer
A scale of severity from 0-4
53
What percent of patients with cancer have a cough
50-75%
54
What type of cough is a call for suspension for cancer
New onset in new or former smoker
55
What percent of people with cancer have dyspnea
25-40%
56
Clinical manifestations of cancer
Cough Dyspnea Hoarseness Systematic effects Adventitious Breath sounds
57
What does a dynamic obstruction look like
Decrease in flow on inspiration or exhalation, but not both
58
What does a fixed obstruction look like
Decreased flow on exhalation and inhalation
59
ABG of a localized lung cancer
pH elevated (patient is compensating) PaCO2: low HCO3: normal or low PaO2: low SaO2/SpO2: low If bicarbonate isn’t
60
ABG of a widespread lung cancer
pH: low PaCO2: elevated HCO3: elevated wnl PaO2: low SaO2/SpO2: low
61
Five surgeries for tumor resection
Pneumonectomy Lobectomy Segmentectomy/ wedge resection Sleeve resection Video-assisted thoracic surgery
62
Three specialized bronchoscopic interventions where therapist play a supporting role
Debunking (reduce size) Stent placement Bleeding control (argon plasma coagulation) heat!!!
63
Which type of tumor is encapsulated
Benign (connective tissue)
64
Recommended screening for cancer
Low dose CT scan
65
How are new discovered pulmonary nodules managed
Monitored.