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MRCOG > Cancer > Flashcards

Cancer Flashcards

1
Q

Cervical cancer IA

A

IA1 = maximum depth </3mm depth
IA2 = max depth 3-5mm

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2
Q

Cervical cancer IB

A

IB1 = >/5mm stromal invasion <2cm
IB2 = >/2cm >4cm
IB3 = >/4cm

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3
Q

Cervical cancer IIA

A

Involvement of upper 2/3 vagina
IIA1 = <4cm
IIA2 = >/4cm

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4
Q

Cervical cancer IIB

A

Parametrial involvement

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5
Q

Cervical cancer IIIA

A

Involvement of lower 1/3 of vagina

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6
Q

Cervical cancer IIIB

A

Extension to pelvic wall or causing hydronephrosis or kidney issues

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7
Q

Cervical cancer IIIC

A

Involvement of lymph nodes
IIIC1: pelvic lymph nodes
IIIC2: para aortic lymph nodes

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8
Q

Cervical cancer IVA

A

Spread to pelvic organs

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9
Q

Cervical cancer IVB

A

Spread to distant organs

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10
Q

Which Onco proteins are related to HPV

A

E6 and E7

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11
Q

Which tumour suppressor proteins do Onco-proteins E6 and E7 inactivate?

A

E6 inactivates p53
E7 inactivates pRb

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MRCOG (11 decks)

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