Cancer Flashcards

1
Q

What is the most common form of pancreatic cancer and where does it form?

A
  • adenocarcinoma

- head of pancreas

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2
Q

How does pancreatic cancer present?

A
  • painless, obstructive jaundice
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3
Q

A new onset of diabetes or a rapid worsening of glycaemic control type 2 diabetes, can be a sign of __________ cancer. Despite good lifestyle measures and medication.

A

pancreatic

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4
Q

NICE guidlines for suspected pancreatic cancer?

A
  • 40+ with jaundice = 2ww referral

- 60+ with weight loss + an additional symptom = direct access CT abdomen

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5
Q

What are the 2 signs of pancreatic cancer?

A
  1. Courvoisier’s law - palpable gallbladder with jaundice is probably pancreatic cancer or cholangiocarcinoma
  2. Trousseau’s sign of malignancy = migratory thrombophlebitis
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6
Q

Investigations for pancreatic cancer

A

Imaging (CT TAP) + histology

  • CA 19-9 tumour marker raised in cholangiocarcinoma or pancreatic cancer
  • MRCP
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7
Q

How is pancreatic cancer managed?

A
  • surgery to remove tumour
  • stents
  • chemo
  • radio
  • whipple procedure
  • modified whipple procedure keeps the pylorus in place
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