Cancer #1 Flashcards

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1
Q

most common cancers in males

A

prostate, lung and bronchus, colon and rectum

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2
Q

most common cancers in females

A

breast, lung and bronchus, colon and rectum

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3
Q

what kind of cancer is the leading cause of cancer death

A

lung cancer

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4
Q

asbestos, ionizing radiations and UVA and UVB cause

A

mesothelioma, lung, leukemia, skin

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5
Q

what are the 2 properties of cancer cells

A

uncontrolled proliferations, colonization to other cell territories

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6
Q

what are the 5 stages of cancer

A

~hyperplasia: increased cell # (normal)
~benign tumor: non aggressive/disruptive, non mobile
~in situ cancer: destructive (changes to local tissue)
~invasive cancer: aggressive/destructive/potential to spread
~metastasis: secondary tumor, growing at distant site

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7
Q

cancer is mainly caused by

A

somatic mutations, as inherited forms of cancer are 5-10% only

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8
Q

is a single mutation sufficient for a cell to become carcinogenic

A

no

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9
Q

what is a passenger mutation

A

ones that do not confer selective advantages

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10
Q

what are driver mutations

A

ones that give acquired abnormal properties

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11
Q

adenomas are cancers of

A

epithelial tissues

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12
Q

sarcomas are cancers of

A

CT

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