Cancer #1 Flashcards
most common cancers in males
prostate, lung and bronchus, colon and rectum
most common cancers in females
breast, lung and bronchus, colon and rectum
what kind of cancer is the leading cause of cancer death
lung cancer
asbestos, ionizing radiations and UVA and UVB cause
mesothelioma, lung, leukemia, skin
what are the 2 properties of cancer cells
uncontrolled proliferations, colonization to other cell territories
what are the 5 stages of cancer
~hyperplasia: increased cell # (normal)
~benign tumor: non aggressive/disruptive, non mobile
~in situ cancer: destructive (changes to local tissue)
~invasive cancer: aggressive/destructive/potential to spread
~metastasis: secondary tumor, growing at distant site
cancer is mainly caused by
somatic mutations, as inherited forms of cancer are 5-10% only
is a single mutation sufficient for a cell to become carcinogenic
no
what is a passenger mutation
ones that do not confer selective advantages
what are driver mutations
ones that give acquired abnormal properties
adenomas are cancers of
epithelial tissues
sarcomas are cancers of
CT