Campylobacter and helicobacter

Question 1

Characteristics of campylobacter

Answer 1

level 2 
curvy, wavy rods
gram-negative 
microaerophilic (O2 and CO2) 
requires nutritious media
so grow at elevated temps
intestine, repor tract

Question 2

helicobacter characteristics

Answer 2

level 2
corkscrew shape = flagella
microaerophilic
stomach and GIT of host

Question 3

virulence of Campylobacter jejuni

Answer 3

flagella
outer membrane adhesion proteins
superoxide dismutase and catalase
cytolethal -distending toxin

Question 4

C, fetus subsp veneralis

Answer 4

host: cattle 
can be silent to clinical presentation 
dz: infertility, early embryonic death 
acquired from outside entering into the vagina (sexual transmission)
tx: natural resolution and vx

Question 5

C. fetus subsp fetus

Answer 5

host: small ruminant, cattle, humans
dz: abortions in final 6 wks of pregnancy
- febrile, vaginal discharge
acquired through ingestion - travels to gall bladder to uterus
highly contagious
tx: antimicrobials, vx

Question 6

C. jejuni subsp jejuni

Answer 6

host: humans, other animals, pigs
dz: gastroenteritis, enterocolitis (H)
infected by ingestion
very low infectious dose
tx: self-limiting

Question 7

C. coli

Answer 7

host: pigs
dz: enterocolitis

Question 8

C. upsalensis

Answer 8

host: dog
dz: eneteritis

Question 9

helicobacter species

Answer 9

host: various
dz: gastritis

Question 10

Guillain-Barre syndrome

Answer 10

rare sequelae (<1/1000 cases) following campylobacteriosis
- GBS is an acute demyelinating disease of the peripheral nerves
no correlation between infection severity and the likelihood of developing GBS

Question 11

Campylobacter spp

Answer 11

take positive fecal cultures with a big grain of salt
- commonly isolated from healthy animals
the exception is young animals <6months with clinical disease