Calculating QALY Flashcards
1
Q
Two Methods for Estimating QALY
A
Direct
- Rating Scale
- Standard Gamble
- Time Trade-off
Indirect
- EQ-5D
- SF-6D
- HUI
- QWB
2
Q
Obtaining QALYs
A
- For each option, sum the Utility Scores * Length of Life
- Assume the same baseline point
3
Q
Calculating Utilities
A
- Develop a description of each disease state or condition of interest
- Choose a method for determining utilities
- Choose subjects who will determine utilities
4
Q
Describing Health State
A
-Use concise language describing health effects expected from the disease state or condition
Include
- Amount of pain/discomfort
- Any restriction on activities
- Time it may take for treatment
- Possible changes in health perceptions
- Any mental changes
5
Q
Choose Determining Utility Method
A
-Ideally ALL methods should include a description of a path from baseline to health that includies one or more health states with specific time periods for states
Main Differences
- How question is framed with certain or uncertain outcomes
- Way subject is asked to respond: choice or sliding scale
6
Q
VAS
A
- Scaling
- Certainty with response
7
Q
TTO
A
- Making a choice
- Certainty with response
8
Q
Standard Gamble
A
- Making a choice
- Uncertainty involved with response
9
Q
Standard Gamble
A
- Certain and uncertain options
- Rest of life with a disease versus intervention that has a chance of death
- P varies for different subjects
- Useful for assessing utilities for chronic conditions
10
Q
TTO
A
- Intended to give comparable scores to SG
- Offered two certain options
- Time x varies between subjects until indifference reached
- Utility weight: x/t
