Calcium Channel Blockers Flashcards
1
Q
Dihydropyridines are selective for _____________
A
Smooth muscle vasodilation
S/E - flushing, dizziness, constipation, gingivial hyperplasia
2
Q
Class - Amlodipine & Nifedipine
A
Dihydropyridines
Use - HTN, Prinzmetal’s angina, Raynaud’s
3
Q
Can cross BBB; useful in post-sub arachnoid hemhorrage to prevent vasospasm
A
Nimodipine
4
Q
What type of channels are blocked?
A
L-type calcium channels
5
Q
_____________ can cause can cause hyperprolactinemia
A
Verapamil
6
Q
Why do calcium channel blockers cause constipation?
A
Ca2+ is a second messenger for gastrin - decreased gastrin, decreased mobility
7
Q
Cardioselective calcium channel blockers
A
Verapimil - V rapper
Dilitizem - Dill taser
