Drug reactions Flashcards
Causes of coronary vasospasm
Cocaine, sumatriptan (serotonin agonist for cluster headaches/migraines), ergot alkaloids
Causes of cutaneous flushing
Vancomycin, Adenosine, Niacin, Ca 2+ channel blockers
VANC
Causes of Dilated cardiomyopathy
Doxorubicin (Adriamycin), Daunorubicin
Causes of Torsade de Pointes
Class III (sotalol) Class IA (quinidine)
Causes of agranulocytosis
Clozapine, Carbamazepine, Colchicine, PTU, Methimazole, Dapsone
“Agranulocytosis Could Certainly Cause Pretty Major Damage”
Causes of aplastic anemia
Chloramphenicol, Benzene, NSAIDs, PTU, Methimazole
Direct Coombs - Positive Hemolytic Anemia
Methyldopa, penicillin
Gray baby syndrome
Chloramphenicol
Hemolysis in G6PD patients
Isoniazid, Sulfonamides, Primaquine, Aspirin, Ibuprofen, Nitrofurantoin
Hemolysis IS PAIN
Megaloblastic anemia
Pheytoin, Methotrexate, Sulfa drugs
Having a blast with PMS
Thrombotic complications
OCPs
C/O Cough
ACEi (use ARB instead)
C/O Pulmonary fibrosis
BLeomycin, Amiodarone, Busulfan
“It’s hard to BLAB when you have pulmonary fibrosis”
C/O Acute Cholestatic Hepatitis, Jaundice
Erythromicin
C/O Focal to Massive Hepatic Necrosis
Halothane, Amanita phalloides (death cap mushroom), Valproic Acid, Acetaminophen
Liver “HAVAc”
C/O Hepatitis
INH
C/O Pseudomembranous colitis
Clindamycin, ampicillin