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Vascular Tone SM > Calcium Channel Blockers > Flashcards

Calcium Channel Blockers Flashcards

1
Q

Nifedipine
MOA

A

Blocks voltage-gated calcium channels in vascular smooth muscles inhibiting calcium influx and thus contraction resulting in vasodilation

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2
Q

Nifedipine
Abs/Distrb/Elim

A

Given orally.
Half-life of nifedipine 2h

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3
Q

Nifedipine
Clinical use

A

Hypertension
Angina pectoris.

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4
Q

Nifedipine
Adverse effects

A

Nausea
Headache
Reflex tachycardia
Peripheral ankle odema

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Vascular Tone SM (6 decks)

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