CAD Flashcards
If EKG is unclear or EKG is not diagnostic - perform
ETT ( exercise tolerance testing). Looking for ST segment depression
Appropriate Exercise during ETT if
Heart rate > 80 % of maximum
Maximum heart rate during ETT
= 220 - patient age
Thallium( nuclear) stress test. Normal myocardium picks up thallium like
Potassium via Na/K- ATPase (similar)
If myocardium is normal -you see on Stress or Dobutamine Echo
Moves on echo
Myocardial Abnormalities on Stress or Dobutamine Echo. If ischemia
Decrease wall motion ( dyskinesis, akinesis, hypokinesis)
Ischemia vs infarction during thallium test or echo
Ischemia is reversible (perfusion) wall motion or thallium uptake between rest and exercise. Infarction is irreversible or “fixed”
What you are looking for during echo or thalium
Reversible changes
If pt can’t exercise
Persantine( dipyridamole) or adenosine with nuclear isotopes ( thallium or sestamibi) or dobutamine in combination with echo
Increases myocardial oxygen consumption, provokes ischemia=> decreases wall motion on echo
Dobutamine
Avoid in asthma pts, inc cAMP
Dipyridamole may provoke bronchospasm
If can’t read EKG( already have ST depression, R or LBBB, pacemaker, digoxin )
Do exercise thallium( decreased uptake of nuclear isotope) or = exercise echo ( decr. Wall motion) .
If can’t exercise do
Dipyridamole thallium test( decreased uptake of nuclear isotope) or =Dobutamine echo ( decreased wall motion)
Stenosis( narrowing) is insignificant if
< 50 % of CAD diameter
Surgery or angioplasty should be done for at least CAD
70% stenosis