C8: Mitral Stenosis Flashcards

1
Q

define MS

A

incomplete opening of the MV during diastole w/ thickened MV leaflets

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2
Q

which valve does rheumatic fever effect first

A

MV

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3
Q

3 layers of the MV leaflets

describe them

A

from ventricle side to atrial side:

fibrosa: provides structural support and stiffness when valve is closed
spongiosa: provides flexibility, contains less dense tissue
atrialis: smooth layer composed of endocardial cells that line the whole atria

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4
Q

which MV leaflet is more complex

how

A

AML, one layer extends mediallu towards the AV to form the aorto-mitral curtain

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5
Q

do both MV leaflets cover the same area of the valve orifice

A

yes, approx…. AML is longer and occupies up 1/3 of the MV annulus, PML is shorter and occupies 2/3 of MV annulus

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6
Q

how are the MV scallops labeled

A

lateral to medial, 1-3

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7
Q

which MV leaflet is more susceptible to MAC

A

PML

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8
Q

3 functions of chordae tendinae

how many are there

A

anchoring the valve
maintain ventricular geometry
prevent prolapse during systole

120

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9
Q

main function of pap muscles

A

contract during systole to hold the valve closed

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10
Q

describe the position and structure of the PM pap muscle

A

on the inferior wall of the LV (seen from PSAX adjacent to the septum)

has 2 bodies that trifurcate into 3 heads

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11
Q

blood supply for PM pap muscle

A

posterior descending A

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12
Q

describe the position and structure of the AL pap muscle

A

on the anterolateral wall of the LV (seen from PSAX near LV free wall)

had 1 body that bifurcated into 2 heads

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13
Q

blood supply for AL pap muscle

A

left anterior descending A and circumflex A

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14
Q

which pap muscle is more susceptible to complications from ischemia or infarction

A

PM pap muscle because it only has 1 artery supplying it

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15
Q

4 etiologies on MS

A
  1. rheumatic fever
  2. degenerative (MAC)
  3. congenital
  4. masses
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16
Q

describe how rheumatic fever causes MS

A

inflammation causes swelling and then scarring of the leaflets, starts at the leaflet tips… will eventually lead to calcifications

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17
Q

how are the commissures effected w/ rheumatic MS

chordae?

A
  • theyre thickened and fibrosed

- matted and shortened (think rheu’matted’ fever)

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18
Q

characteristic appearance of MV w/ rheumatic MS

A

fish mouth

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19
Q

describe how degeneration (MAC) causes MS

A

calcification of the MV annulus that usually starts at the posterior basal annulus and progresses inwards to the leaflets

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20
Q

which area of the MV is usually spared w/ MAC

A

leaflet tips

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21
Q

MAC is associated w/ which conditions

A
HTN
diabetes
hypercalcemia
age
Marfan's syndrome
renal dialysis
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22
Q

describe the congenital causes of MS

A

usually involves subvalvular apparatus like a single pap muscle

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23
Q

term for a single pap muscle

A

parachute MV

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24
Q

what types of masses may cause MS

A

large MV vegetation from bacterial endocarditis

large LA myxoma

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25
Q

describe the pathophysiology of MS in the heart

A

reduce opening of MV leads to increased LA pressure, this increases PV, lung and PA pressure and evetually increases RVSP and RA press which leads to TR

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26
Q

describe the pathophysiology of MS in body

A

increase RH press leads to increase venous press w/ hepatomegaly, pedal edema, sometimes distended JVs

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27
Q

which arrhythmia is common w/ severe MS

A

A fib

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28
Q

symptoms of MS are similar to which other condition

A

backwards HF

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29
Q

w/ MS, does LV and LA pressure equalize during diastasis

why

A

no, you’ll lose diastasis and will see forward flow into the LV instead

theres a smaller opening for blood to pass through so press takes longer to drop

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30
Q

what kind of murmur is heard w/ MS

A

diastolic rumble at apex

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31
Q

3 symptoms of MS

A

dyspnea
reduced execise capacity (SOBOE)
fatigue

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32
Q

what factors can make the symptoms of MS worse

A
any increase in HR or CO:
fever
anemia
preg
hyperthyroidism
rapid arrhythmia
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33
Q

complications of MS

A
a fib
atrial enlargement
blood clots and thromboembolism
hempotysis
endocarditis
34
Q

what is hempotysis

A

frothy, bloody sputum in the lungs

35
Q

w/ MS would you measure the thickness of the valve leaflets

how do you do this

A

yes

zoom on the MV, scroll until valve is at maximal opening and well seen, measure both leaflets

36
Q

4 important doppler parameters to grade MS severity

A

mean trans-mitral press gradient (important) - trace VTI
MV area - measure PHT
pulmonary artery pressures
MR

also do continuity equation

37
Q

rheumatic MS 2D appearance

A

commissural fusion: leads to doming of the AML and restricts the movement of the PML

restricted motion

38
Q

whats the characteristic MV appearance of rheumatic MS

A

hockey stick

39
Q

w/ the MV have the double bump w/ MS

A

no

40
Q

norm value for MV leaflet thickness

A

1-2 mm

41
Q

characteristic of severe MAC

A

posterior shadowing in and behind the LA

42
Q

can the chordae be effected by MAC

A

yes

43
Q

another term for MAC

A

mitral sclerosis

44
Q

what is a cor triatriatum sinister

A

a perforate LA membrane that impedes flow of blood from LA to LV and causes a gradient b/w the LA and LV

45
Q

are there any symptoms unique to cor triatriatum sinister

A

no, same as other types of MS

46
Q

is the MV usually norm w/ cor triatriatum sinister

A

yes

47
Q

what does the severity of the cor triatriatum sinister depend on

A

the size of the perforation(s) in the membrane, eg. how easily blood can get through

48
Q

describe a LA myxoma

A

most common primary tumor in the heart, most are benign… often attached to the fossa ovalis w/ a peduncle/foot

49
Q

US appearance of a LA myxoma

A

globular, fine speckld appearance

50
Q

what can happen if a LA myxoma is large

A

prolapse into the MV during diastole and cause functional MS

51
Q

what is a parachute MV

associated w/ which syndrome

A

a single pap muscle that often placed too far superior in the LV

shone’s syndrome

52
Q

5 anomalies of shone’s syndrome

A
supravalvular ring
parachute MV
subAO stenosis
bucuspid AV
Ao coarctation
53
Q

how do you do MV planimetry

is it accurate

A

zoom on the MV in PSAX and trace around the blood tissue interface

can be the most accurate method to quantify MS if done properly

54
Q

what does the accurate on MV planimetry depend on

A

ability to clearly see the orifice
tracing orifice directly at leaflet tips
gain settings
operator skill

55
Q

if you transect the MV above the leaflet tips, how will that effect MV planimetry

A

will underestimate its severity

56
Q

MS on M-mode

A

reduced excursion on MV, loss of double bump and diastasis, tracing will be brighter

57
Q

when is the only time we do colour on the MV in PSAX

A

if theres MR

58
Q

is you have MS, would your MV inflow PW be accurate for assessing diastolic dysfunction

what should you do

A

no, MS will cause the flow to be high velocity

reply on TDI tracing instead

59
Q

PW will alias over what velocity

A

2m/s

60
Q

how do we get MV mean press gradient

how does the machine calculate it

A

use CW through the MV inflow and trace the waveform…

machine will give you the mean PG by applying 4(v^2) to each point on the trace and avg the values… this is done b/w the waveform is not parabolic and the PG varies throughout diastole

61
Q

how can HR effect the MV mean press gradient value

what about preload

A

Lower HR will result in a smaller waveform for mean PG is underestimated

can be over or underestimated w/ changes in preload

62
Q

MV mean press gradient value for mild MS

severe

A

mild: < 5 mmHg
severe: >10 mmHg

63
Q

how does MS effect PHT

A

the rate of atrial emptying in slowed due to a narrowed orifice which prolongs the decline on early diastolic PG b/w the LA and LV… PHT will be prolonged

64
Q

how are MV area and PHT related

A

inversely… press fall slower w/ a more stenotic valve b/c the PG is maintained for longer

65
Q

formula for MV area

A

MV Area = 220 / PHT

66
Q

how is DT effected w/ MS

A

prolonged, press fall slower w/ a more stenotic valve b/c the PG is maintained for longer

67
Q

as MS gets more severe, how can the MV inflow A wave change

A

gets merged w/ the e wave

68
Q

how do we measure MV area w/ the continuity method

A

calculate SV through the AV/a control valve using the LVOT and LVOT VTI, then we can measure the VTI of the MV inflow and extrapolate and MV area from that

69
Q

can you use to continuity method to measure MS if you have mod-severe MR or AR

A

no, use PHT instead, or PISA, or use a different valve for the control valve

70
Q

continuity equation formula for MV area

A

MVA = (pie (r^2) x VTI) of LVOT / VTI of MV

you need LVOT diameter
LVOT PW trace
MV CW trace

71
Q

2 sources of error when calculating MV area w/ continuity equation

A

incorrect measurement of LVOT area

incorrect doppler angle

72
Q

continuity equation to measure MV area is less accurate in which conditions

when would you not use this meathod

A

significant MR, AR

ASD or other intracardiac shunt

73
Q

which method for measuring MV area is the quickest

A

PHT

74
Q

does TTE or TEE have better sensitivity for blood clots

A

TEE. TTE has high specificity but low sensitivity

75
Q

why is it important to measure RVSP w/ MS

A

it tells you how the heart in handling the MS

76
Q

can MS cause pulmonary hypertension

is it reversible

A

yes

at first, longstanding PHT causes irreversible increases and wont resolve even w/ MV surgery

77
Q

what does timing of MV surgery depend on

A

LV/LA and Rv function

78
Q

pharmacologic treatment for MS

A

beta blockers
diuretics
anticoagulation
anti-arrhythmics

you would try these before surgery

79
Q

surgical treatment for MS

A

valve repair - cant be done if the cause is calcific
balloon valvuloplasty
commissurotomy (causes regurg)

valve replacement
bioprosthetic
mechanical
percutaneous

80
Q

norm MV area

A

4-6 cm^2

81
Q

MV area for mild MS

severe

A

mild: >1.5 cm^2
severe: < 1 cm^2

same as mild/severe AS