C13: Pulmonary hypertension Flashcards
define PHT
characterized by evaluated pulmonary arterial pressure secondary to RV failure
can both pulmonary disease and disease of the RV muscle cause PHT
yes
w/ PHT, what changes are seen to systolic and diastolic function of the RV
reduced FAC, TAPSE and S prime
diastolic usually abnormal
2 categories of causes of PHT
describe them
pre-capillary:
before the lungs….
-congenital heart disease - shunts
-respiratory diseases - PE, PPS
post-capillary: after the lungs... -MV disease, AV disease -myoxoma -cor triartiatum -PV compression -myocardial disease -systemic HTN
are most causes of PHT pre or post capillary causes
post
PHT values for:
PCWP
SPAP
MPAP
PCWP - > 18mmHg ( > 15 mmHg is abnormal)
SPAP = RVSP if no obstruction - >35 mmHg (30-35 is borderline)
MPAP - >/= 25 mmHg
respiratory symptoms for PHT
SOB
cough
wheezing
hemoptysis - press is so high, blood is getting into the air passageways
intercostal retraction - increased muscle mass due to difficulty breathing
associated cardiac symptoms w/ PHT
palpitations/arrhythmias chest pain SOB orthopnea syncope
signs of RHF
norm mean pressure in the RA and IVC
0-4 mmHg
norm pressure in the RV and PA
< 25 / < 10 (systolic and diastolic)
same for both
is TV pg the same as 4(v)^2
yes
cardiac causes of RHF
LHF pulmonary valve stenosis RV infarction massive TR congenital malformations shunts
when the R heart fails, what always happens to the pulmonary pressures
they always go up
2 pulmonary/lung causes of elevated R heart pressures
parenchymal
vascular
parenchymal, pulmonary causes of elevated R heart pressures
COPD
interstitial lung disease
adult respiratory distress syndrome
chronic lun infection
vascular, pulmonary causes of elevated R heart pressures
PE
primary pulmonary HTN
describe the pathophysiology of cor pulmonale
progressively increasing chronic pressure overload of the RV as it ejects into the high resistance vascular bed
how does cor pulmonale initially affect the RV?
how does it progress
initially: RVH…
…then RV dilation and TR from annular dilation…. then RV failure
common cause of PE
DVT that became an emboli
what is a saddle emboli
clot that lodges @ the bifurcation of the PA
in patients w/ a shunt (ASD/VSD/PFO) who have developed P HTN, what can happen to the direction of the shunt
What is it called when thIs happens?
it can be reversed (going from right to left) due to very high pulmonary pressures… or could be biphasic depending on which press is higher
Eisenmengers syndrome
how does chronic volume overload of the RV affect the lungs
permanent lung damage which raises pulmonary pressures and RVSP
anything that causes pressure or volume overload of the RV will also cause what
RVH and RV and TV annular dilation (TR)
chronic evaluation of the RT heart pressure often lea to what 3 things
dilated coronary sinus
reopening of a PFO (acquired PFO)
dilated main PA