C5 - Plasma membrane Flashcards
What is compartmentalisation
Formation of separate membrane-bound areas in cells
What is a plasma membrane
All the membrane of cells which have same basic structure described by fluid mosaic model
What is a phospholipid bilayer
Arrangement of phospholipids found in cell membranes
Hydrophilic phosphate heads form inner and outer surface of membrane
Hydrophobic phosphate tails form hydrophobic core
What is the fluid mosaic model
Model of the structure of a cell membrane in which phospholipids within the bilayer are free to move and proteins are embedded in various positions
Phospholipid bilayer diagram
Fluid mosaic model diagram
What is a membrane protein
Protein component of cell-surface membrane
What are the two types of membrane proteins
Intrinsic: embedded through both layers of a membrane, contain amino acids with hydrophobic R groups than interact with hydrophobic core
Extrinsic: present of one side of bilayer, contain hydrophilic R groups and interact with polar heads
What are examples of intrinsic proteins
Channel proteins
Carrier proteins
Glycoproteins
What is a channel protein
Intrinsic protein that provides hydrophilic channel allowing passive movement of polar ions and molecules down a conc gradients through membranes
What are carrier proteins
Intrinsic proteins that transport substances through membrane actively, against a concentration gradient
What are glycoproteins and their role
Intrinsic proteins embedded in cell surface membrane with attached carbohydrate chains
Play a role in cell adhesion and as receptors for chemical signals (cell signalling- response triggered after chemical bound to receptor)
What are glycolipids and their function
Lipids attached to carbohydrate chains
Cell markers/antigens - recognised by immune system as self / non-self
What is cholesterol
Lipid with hydrophilic and hydrophobic end
Regulates fluidity of membrane and adds stability by positioning itself between phospholipids and pulling them to her
Prevent phospholipids from getting to close and crystallising
What affect does temperature have in the cell membrane
Phospholipids have increased KE
Move more
Membrane becomes more fluid and loses its structure
What happens to membrane permeability when temp inc
Permeability increases
What happens to carrier and channel proteins when temp inc
Denature (membrane permeability inc)