c3 Flashcards
Mechanisms of Evolutionary change
Mutation, Gene flow, genetic drift, natural selection
changes not just on the gene but also in biomolecule components causing them to mutate chemically
mutation
movement of one representative organism carrying a specific gene
gene flow
isolation of certain populations from an entire population of organism which cause change in gene frequency
genetic drift
most common mechanism; happens on a natural habitat affected by habitats, habits, relationship with other organisms or population
natural selection
changes in DNA which could affect subsequent translation , transcription in central dogma (change in information of cell)
mutation
hereditary material of life that carries genetic information from gen to gen
DNA
types of mutation
germline mutation
somatic mutation
This gene mutation is a substitution of a single base
point mutation
type of point mutation where it has no effect on protein sequence; substitution in the 3rd base
silent
type of point mutation where it results in an amino acid substitution; substitution in 2nd base
Misense
substituted a stop codon for an amino acid; single base subs but yield stop codon
nonsense
Gene mutation where there is insertion/deletion of one or more bases
Frameshift mutation
DNA template ready by mRNA and RNA in 3 bases; reading is not selective; shift in reading of mRNA and RNa
Frameshift mutation
In frameshift mutation, one or more bases are added/deleted in DNA sequence causing the reading frame to ____ which results in ____ and ________.
shift; shortened; non functional protein sequence
chromosome mutation
the chromosome structure become influenced by:
1. change in amount of genetic information in chromosome because of:
_______
_______
- similar amount of genetic information but the materials are rearranged
______
______
- Deletion
Duplication - Inversion
Translocation
Example of
Deletion:
Duplication:
Deletion: Cri du chat
Duplication: Charcot-Marie-Tooth disease
change in number of chromosome
Genome mutation
-deletion/addition of 1 chromosome
-selective ang pag dagdag
more common in humans
Monosomy and trisomy
Aneuploidy
-addition of sets of chromosome
lahat nadadagdagan
rare in humans
polyploidy
A ______ can have a large effect, but in many cases, evolutionary change is based on the _______
single mutation
accumulation of many mutations
T or F
1.Mutations are non random
2.Not all mutations matter to evolution
1.F
2.T
2 causes of mutations
- DNA fails to copy accurately
- external influences
Any movement of individuals in a population to another population; any movement of individuals and/or the genetic material they carry from one population to another; gene migration
gene flow
Gene flow affect evolution by ____
introducing a new gene
2 types of gene flow
Vertical gene transfer
horizontal gene transfer
A type of gene flow where it involves two population of same species; mediated by reproduction;
Vertical gene transfer
A type of gene flow where it involves two different species; known as lateral gene transfer; decreases
horizontal gene transfer
- increases genetic variation of population
2.genetic differences between two different species
1.Vertical gene transfer
2.horizontal gene transfer
Restrictions of gene flow
- physical barriers
- incompatible reproduction behaviors
- allele frequencies of a population change over generations due to chance or sampling error
genetic drift
drift ultimately to the entire population, becoming their original ancestor of that population; reduce in variation of gene since other gene variations are wiped out
Bottleneck effect