C.14/15 - Genetics Flashcards
True Breeding Character/Trait
Plants that produce offspring of the same variety when they self-pollinate
P, F1, and F2 Generations
P - The true-breeding parents
F1 - The hybrid offspring of the P generation
F2 - When F1 individuals self-pollinate or cross- pollinate with other F1 hybrids
Dominant and Recessive Alleles
If two alleles at a locus differ, then one (the dominant allele) determines the organism’s appearance, and other (the recessive allele) has no noticeable effect
Genotype and Phenotype
Different effects of dominant and recessive alleles do not always reveal an organisms genetic composition. Must distinguish between an organism’s phenotype, or physical appearance, and its genotype, or genetic makeup.
Testcross
Breeding the mystery individual with a homozygous recessive individual. If any offspring display the recessive phenotype, the mystery parent must be heterozygous
Law of Segregation
Two alleles for a heritable character segregate during gamete formation and end up in different gametes, so an egg or a sperm gets only one of two alleles. This corresponds to distribution of homologous chromosomes to different gametes in meiosis
Accounts for 3:1 ratio observed in F2 generation.
Law of Independent Assortment
Alleles segregate independently of each other during gamete formation, only applies to genes on different, non-homologous chromosomes (Genes located near each other on the same chromosome tend to be inherited together)
Complete Dominance
Occurs when phenotypes of the heterozygote and dominant homozygote are identical (Purple/White Pea Plant Flowers)
Incomplete Dominance
The phenotype of F1 hybrids is somewhere between the phenotypes of the two parental varieties (White/Red Roses make Pink)
Codominance
Two dominant alleles affect the phenotype in separate, distinguishable ways (White and Black Cows make Cows with white and black patches)
Pleiotropy
Genes that have multiple phenotypic effects. Responsible for the multiple symptoms of certain hereditary diseases, such as cystic fibrosis and sickle-cell
Epistasis
A gene at one locus alters the phenotypic expression of a gene at a second locus. For example, in Labrador retrievers and many other mammals, coat color depends on two genes; One gene determines pigment colour, another gene dictates whether pigment will be deposited in hair