Buzzwords Phase 0 Part 3

Question 1

Most common vitamin deficiency worldwide

Answer 1

Vitamin A deficiency

Question 2

Earliest sign of vitamin A def

Answer 2

Loss of sensitivity to green light

Question 3

Vitamin D can be used to prevent infections cuased by

Answer 3

M tb

Question 4

Vitamin D has antiproliferative effects vs

Answer 4

Colon CA
Breast CA
Prostate CA

Question 5

Faeftures of scurvy

Answer 5

Swollen gums
Bleeding diathesis
Poor wound healing
Corkscrew hair

Question 6

Wenicke encephalopathy

Answer 6

Ataxia
Confusion
Ophthalmoplegia

Question 7

Korsakoff

Answer 7

Personality changes
Amnesia
Confabulation
Hallucination

Question 8

Damaged structures in wenicke-korsakoff syndrome

Answer 8

Mammillary bodies

Medial dorsal nucleus of thalamus

Question 9

B2 def

Answer 9

Cheilosis

Corneal vascularization

Question 10

Tryptophan and niacin

Answer 10

1mg niacin = 60mg tryptophan

Question 11

Effect of niacin on lipid profile

Answer 11

Dec VLDL

Inc HDL

Question 12

Niacin defficiency dermatitis

Answer 12

Casal necklace (C3/C4)

Question 13

Conditions increasing risk of B3 def

Answer 13

Hartnup dse
Isoniazid use
Carcinoid syndrome
Corn-based diet

Question 14

B3 toxicity

Answer 14

Facial flusing
Livertoxicity
Podagra

Question 15

B5 deficiency

Answer 15

Gopalan’s burning feet syndrome

“Nutritional melalgia”

Question 16

Only enz needing B6 which is not associated with amino acid metabolism

Answer 16

Glycogen phosphorylase

Question 17

Site of B9 and B12 absorption

Answer 17

B9: jejunum
B12: ileum

Question 18

B9 vs B12

Answer 18

B12: increased methymalonic acid

Question 19

Salivary protein that binds to freed Vitamin B12 in the stomach

Answer 19

Haptocorrin

Transcobalamin I

Question 20

Receptors that allow the endocytosis of B12-IF complex

Answer 20

Cubilin receptors of ileal enterocytes

Question 21

Transport protein of vitamin B12 in circulation

Answer 21

Transcobalamin II

Question 22

Site of iron absorption

Answer 22

Proximal duodenum

Question 23

Ferroportin

Answer 23

Transfers iron across the basolateral membrane of enterocytes to the circulation

Question 24

Triad of hemochromatosis

Answer 24

Bronzing
Cirrhosis
DM

Question 25

Wilson disease

Answer 25

Kayser-Fleischer ring depostion in the descemet membrane of cornea

Question 26

Decreased zinc absorption

Answer 26

Acrodermatitis enteropathica

AR

Question 27

Stabilizes insulin

Answer 27

Zinc

Deficiency may cause impaired spermatogenesis

Question 28

Potentiates insulin

Answer 28

Chromium

Question 29

Endemic, reversible cardiomyopathy seen in patient with Se deficiency

Answer 29

Keshan cardiomyopathy

Question 30

Prominent feature of Se toxicity

Answer 30

Garlic breath