Buzzwords Flashcards by Landon Riggs

Q

BCR-ABL

A

Chronic yelogenous Leukemia (CML)

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Q

ERBB1

A

Lung Adenocarcinoma

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Q

ERBB2

A

Breast Carcinoma

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Q

ALK

A

Adenocarcinoma of the lung

Neuroblastoma

Lymphomas

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Q

C-MYC

A

Burkitt Lymphoma

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Q

NMYC

A

Neuroblastoma

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Q

HGF

A

Hepatocellular Carcinoma, Thyroid Cancer

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Q

LMYC

A

Small Cell lung cancer

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Q

SHH

A

Meduloblastoma

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Q

Familial TP53 mutation

A

Li-Fraumeni Syndrome

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Q

HPV

A

Squamous Cell Carcinoma

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Q

APC. what is it and what cancers are part of it?

A

GATEKEEPER OF COLONIC NEOPLASIA

Adenomatous Polyposis / Adenomas

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Q

CDH1

A

Familial Gastric Carcinoma

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Q

NF1

A

Neurofibromatosis type 1

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Q

NF2

A

Neurofibromatosis type 2

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Q

WT1

A

Wilms Tumor

Q

PTCH

A

Gorlin Syndrome –> basal cell carcinoma and meduloblastoma

Q

VHL

A

Pheochromocytoma, renal cell carcinoma

Q

BRCA1/BRCA2

A

Breast Cancer

Q

BCL2

A

B cell lymphoma (due to 14;18 translocation)

Q

Leukoplakia

A

Squamous Cell Carcinoma

Q

Benign neoplasm with high risk to become malignant

A

colon villous adenoma

Q

most common skin cancers

A

Basal Cell carcinoma > Squamous cell carcinoma >

Q

Most common lung cancers

A

Adenocarcinoma

Squamous Cell carcinoma

Q

PDGF

A

Glioblastomas

Q

BRAF (3)

A

Hairy cell leukemia

melanoma + colon carcinoma

Q

(14;18)(q32;q21) translocation

A

follicular lymphoma translocation