Buzzwords Flashcards

1
Q

BCR-ABL

A

Chronic yelogenous Leukemia (CML)

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2
Q

ERBB1

A

Lung Adenocarcinoma

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3
Q

ERBB2

A

Breast Carcinoma

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4
Q

ALK

A

Adenocarcinoma of the lung

Neuroblastoma

Lymphomas

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5
Q

C-MYC

A

Burkitt Lymphoma

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6
Q

NMYC

A

Neuroblastoma

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7
Q

HGF

A

Hepatocellular Carcinoma, Thyroid Cancer

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8
Q

LMYC

A

Small Cell lung cancer

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9
Q

SHH

A

Meduloblastoma

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10
Q

Familial TP53 mutation

A

Li-Fraumeni Syndrome

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11
Q

HPV

A

Squamous Cell Carcinoma

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12
Q

APC. what is it and what cancers are part of it?

A

GATEKEEPER OF COLONIC NEOPLASIA

Adenomatous Polyposis / Adenomas

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13
Q

CDH1

A

Familial Gastric Carcinoma

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14
Q

NF1

A

Neurofibromatosis type 1

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15
Q

NF2

A

Neurofibromatosis type 2

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16
Q

WT1

A

Wilms Tumor

17
Q

PTCH

A

Gorlin Syndrome –> basal cell carcinoma and meduloblastoma

18
Q

VHL

A

Pheochromocytoma, renal cell carcinoma

19
Q

BRCA1/BRCA2

A

Breast Cancer

20
Q

BCL2

A

B cell lymphoma (due to 14;18 translocation)

21
Q

Leukoplakia

A

Squamous Cell Carcinoma

22
Q

Benign neoplasm with high risk to become malignant

A

colon villous adenoma

23
Q

most common skin cancers

A

Basal Cell carcinoma > Squamous cell carcinoma >

24
Q

Most common lung cancers

A

Adenocarcinoma

Squamous Cell carcinoma

25
Q

PDGF

A

Glioblastomas

26
Q

BRAF (3)

A

Hairy cell leukemia

melanoma + colon carcinoma

27
Q

(14;18)(q32;q21) translocation

A

follicular lymphoma translocation