Buzzword Cell Types and Their Disease

Question 1

Smudge Cell

Answer 1

Chronic Lymphoblastic Leukemia (CLL)

Question 2

Hairy Cell

Answer 2

Hairy Cell Leukemia

Question 3

Tear-Drop Erythrocyte

Answer 3

Primary Myelofibrosis

Question 4

Bite cell or Heinz Body

Answer 4

G6PD Deficiency

Question 5

Ballerina Skirt or Down Cell

Answer 5

EBV, Burkitt’s Lymphoma

Question 6

Buttock Cell

Answer 6

Follicular Non Hodgkin’s Lymphoma

Question 7

Auer Rods

Answer 7

Acute Myelogenous Leukemia

Question 8

“Owl Eye” in Lymph = Reed-Sternburg Cells

Answer 8

Hodgkin’s Lymphoma

Question 9

Starry Sky Histology

Answer 9

Hodgkin’s Lymphoma

Question 10

Cerebriform T Cells

Answer 10

Sezary Syndrome

Question 11

Flower Pedal Nucleus

Answer 11

HTLV-1 T cell Leukemia

Question 12

Howell-Jolly Bodies

Answer 12

Sickle Cell Anemia

Question 13

Bence-Jones Proteins

Answer 13

Multiple Myeloma

Question 14

Spherocytes

Answer 14

Hereditary Spherocytosis or Autoimmune Hemolytic Anemia

Question 15

Schistiocytes

Answer 15

Microangiopathic Hemolytic Anemia (TTP/HUS/DIC)

Question 16

Target Cells

Answer 16

Thalassemias (any symptomatic, alpha, beta)

Question 17

Basophilic Stippling

Answer 17

Myelodysplastic Syndromes (cytopenias), alpha thalassemi, and Lead Poisoning

Question 18

Ring Sideroblasts

Answer 18

Sideroblastic Anemia