BUZZ3 Flashcards

1
Q

Pneumonia: CBC

A
  • Increased WBC (NV: 4500 -
    11000)
  • Increased Neutrophils (NV:
    2500 - 8000)
  • Decreased Lymphocytes (NV:
    1000 - 4800)
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2
Q

Gram +, lancet-shaped

A

Streptococcus pneumoniae

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3
Q

Antibiotic of choice for
pneumonia caused by
Streptococcus
pneumoniae

A

No co-morbid illness:
Amoxicillin (DOC)
Extended macrolides
(azithromycin, clarithromycin)

Stable co-morbid:
B- lactam/BLIC combination
2nd generation Cephalosporins
+/- extended macrolides

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4
Q

40/M with CC: DOB
(+) fever, dry cough for 5
days; PE: crackles at
both bases & right mid
lung fields
Expected PE findings

A
  • RR of 32/min
  • HR of 120/min
  • Apical S3 or 3rd heart sound
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5
Q

40/M with CC: DOB
(+) fever, dry cough for 5
days; PE: crackles at
both bases & right mid
lung field
Expected ABG findings

A
  • Oxygen saturation of 80%
  • pH of 7.45
  • Partial pressure of oxygen of
    55 mmHg
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6
Q

40/M with CC: DOB
(+) fever, dry cough for 5
days; PE: crackles at
both bases & right mid
lung field
PaO2/FiO2 ratio

A

150

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7
Q

Differential diagnoses
for 52/M, smoker,
hypertensive, diabetic
(+) severe, crushing
chest pains, cold sweats,
shortness of breath 1-hr
duration

A
  • Acute pulmonary embolism
  • Acute massive myocardial
    infarction
  • Acute aortic dissecting
    aneurysm
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8
Q

Possible ECG findings
for 52/M, smoker,
hypertensive, diabetic
(+) severe, crushing
chest pains, cold sweats,
shortness of breath 1-hr
duration

A
  • 3-4mm ST elevation in V1-V6
  • 3-4mm ST depression in V1-V6
  • Diffusely low QRS voltages
    with pathologic Q waves
  • T wave inversion in V1-V5, I,
    AVL, II,III, AVF
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9
Q

52/M, smoker,
hypertensive, diabetic
(+) severe, crushing
chest pains, cold sweats,
shortness of breath 1-hr
duration
Trop I = 0.40 ng/ml; BP:
80/60; HR: 120 bpm
Most appropriate
intervention

A

Percutaneous coronary
intervention

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10
Q

Case: HF in CKD?
Values expected in the
case

A
  • Hyperkalemia
  • Hypernatremia
  • Hypertriglyceridemia
  • Elevated HbA1c
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11
Q

Anti-diabetic drug to be
avoided if the estimated
GFR is
29/ml/min/1.73/m2

A

Metformin

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12
Q

Recommend renal
replacement therapy

A

GFR less than
15ml/min/1.73/m2

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13
Q

Diarrhea due to cholera

A

Secretory diarrhea

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14
Q

Ion lost most
significantly in cholera

A

Sodium

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15
Q

Intestinal fluid secreted
in cholera

A

Isotonic

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16
Q

Diarrhea associated
with bowel movement
of 6 or more per day

A

Secretory diarrhea

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17
Q

Diarrhea associated
with inhibition of
absorption in the gut

A

Osmotic diarrhea

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18
Q

Diarrhea caused by
ingestion of excessive
sugar or salt

A

Osmotic diarrhea

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19
Q

Elderly patient rushed to
ER presenting with sudden
on dyspnea and orthopnea
preceded by chest
discomfort
PE: apical S3, high-pitched
blowing systolic murmur,
bilateral crackles

A

Acute mitral regurgitation

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20
Q

Most likely cause of acute
mitral regurgitation in the
case above

A

Ischemic papillary muscle

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21
Q

Acute mitral
regurgitation
management

A
  • Diuretics
  • Beta-blockers
  • ACE inhibitors
  • Digitalis
  • Intravenous vasodilator
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22
Q

Serum amylase and
lipase in acute
pancreatitis

A
  • Lipase is more sensitive to
    pancreas and remains
    elevated longer
  • Serum lipase rises within 3-6
    hours from onset of
    pancreatitis
  • Have no role in assessing
    disease severity
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23
Q

Normal serum amylase
in acute or chronic
pancreatitis

A

Suppression of pancreatic
zymogens or proenzymes

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24
Q

Falsely elevated serum
amylase

A

Salivary gland disease
Bowel obstruction, infarction
Perforated ulcer

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25
Q

Confirm the presence of
a nodule and assess the
status of thyroid gland

A

Thyroid ultrasound

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26
Q

Evaluate the physiologic
function of thyroid
nodules

A
  • TSH assays: assessment of thyroid
    function
  • Antithyroid antibodies: determine
    etiology of thyroid dysfunction
  • Thyroid UTZ: diagnosis and
    evaluation of nodular thyroid disease
  • Calcitonin test: marker for
    medullary thyroid carcinoma
  • Fine needle aspiration: most
    accurate test for determining
    malignancy
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27
Q

Detection of metastases
of thyroid cancer

A

Scintigraphy

28
Q

51/F, lost to follow up
with her endocrinologist
Erratically taking
Methimazole
Presents with acute
onset of restlessness
and agitation, confusion,
vomiting and diarrhea

A

Thyroid storm

29
Q

Expected findings in
thyroid storm

A
  • Pyrexia
  • CNS alterations (agitation,
    delirium, psychosis, seizure, coma)
  • GI dysfunction (diarrhea,
    jaundice)
  • Tachycardia
  • CHF
30
Q

Management for thyroid
storm

A
  • Stop production of thyroid
    hormone: PTU, methimazole,
    hydrocortisone
  • Block peripheral effect of
    thyroid hormone: propranolol
  • Inhibit hormone release: SSKI,
    sodium iodide
31
Q

Most common extra
articular
manifestation of
ankylosing spondylitis

A

Anterior uveitis (20-30%)
Others:
* Inflammatory bowel disease
* Heart conduction disturbances
* Aortic insufficiency
* Psoriasis
* Renal abnormalities
* Osteoporosis
* Vertebral fractures

32
Q

Minimum size of
kidney stone that can
block ureter

A

8mm
(Ureteral diameter is 5-8mm)

33
Q

Anemia of
inflammation usually
associated with

A

Cancer-related anemia
a.k.a. Anemia of chronic disease

34
Q

Most common type of
hallucination in
psychotic patients

A

Auditory hallucinations

35
Q

Specific treatment for
dysuria caused by UTI

A

Phenazopyridine

36
Q

Lymphocyte cells
commonly associated
in lymphocytic
leukemia

37
Q

Most common cause of
uncontrolled BP
elevation in secondary
hypertension

A

Renovascular stenosis

38
Q

OSAHS is likely
contributory to the
following
comorbidities

A
  • Pericardial effusion, pulmonary
    hypertension, or right-sided
    heart failure
  • NAFLD
  • Refractory hypertension,
    systemic hypertension,
    coronary artery disease, cardiac
    arrhythmias, heart failure and
    stroke
  • Metabolic syndrome and Type 2
    diabetes
  • Neuropsychiatric dysfunction
39
Q

Minimum duration of
productive cough in
acute bronchitis

A

At least 3 months in each of 2
consecutive years

40
Q

Rapid correction of
hyponatremia may
lead to

A

Osmotic demyelination syndrome
(ODS), previously known as
Central Pontine Myelinolysis
(CPM)

41
Q

Acute gouty arthritis

A
  • Higher vitamin C intake is
    independently associated with a
    lower risk of gout. Supplemental
    vitamin C intake may be beneficial
    in the prevention of gout.
  • negatively birefringent needleshaped
    monosodium urate
    crystals in aspirated joint fluid
  • occurs commonly in beerdrinkers
    and meat eaters
  • blood uric acid levels may be
    normal during an attack
42
Q

Viral or idiopathic
pericarditis treatment

A
  • Aspirin or Ibuprofen
  • Colchicine
  • Corticosteroids
43
Q

Most predominant
underlying cause of
acne vulgaris

A

Genetic predisposition

44
Q

95% of cells in the
epidermis

A

Keratinocytes

45
Q

Effective treatment in
acute severe allergic
reactions

A
  • Epinephrine (adrenaline) –
    reduction of body’s allergic response
  • Oxygen – to aid in breathing
  • IV antihistamine and
    corticosteroids – reduction of
    inflammation of air passages and
    improvement of breathing
  • Beta-agonists – relief of breathing
    symptoms
46
Q

Tried to retard
progression of
rheumatoid arthritis

A

Hydroxychloroquine

47
Q

HIV / AIDS

A

Prolonged asymptomatic stage after
initial infection
Median time: ~ 10 years

48
Q

Fast phase nystagmus
Peripheral vestibular
lesion

A

Cold water in the ear, which causes
ipsilateral vestibular dysfunction,
produces nystagmus to the opposite
side
(Mnemonic: “cows”)

49
Q

Supportive treatment
of acute dengue

A
  • Maintaining hydration with oral or
    parenteral fluids
  • Paracetamol as antipyretic or analgesic
  • Platelet transfusion in more severe cases
    of thrombocytopenia
  • NSAIDs are contraindicated for
    management of pain and fever because of
    potential increase in bleeding risk
50
Q

HbA1c goal for
patients with Type 2
DM

51
Q

Antibody in allergic
reactions

52
Q

Dengue vaccine
indications

A

9 to 16 years old with laboratoryconfirmed
previous dengue
infection and living in endemic
areas

53
Q

Allergic reactions

A

Immunoglobulin binds to allergen
and mast cells

54
Q

Metabolic syndrome

A

Criteria:
* Central obesity – Waist circumference
>102cm (M) or >88cm (F)
* TG ≥ 150 mg/dL or use of specific
medication
* HDL <40mg/dL (M) or <50mg/dL or use of
specific medication
* BP ≥130 systolic or ≥85 diastolic or use of
specific medication
* ≥100 mg/dL or use of specific medication
or previously diagnosed T2DM

55
Q

Most common primary
cancer that cause
brain metastasis

A

Lung cancer

56
Q

Prevention of oral
thrush in patients on
inhaled steroids

A

Rinse mouth with water
immediately after using inhaler

57
Q

Most common
offending organisms in
infective endocarditis

A

Streptococci and Staphylococci

58
Q

Sjögren syndrome

A

Dry skin, mouth, eyes, nose
Confirmed by tissue biopsy
Avoid antihistamines like
diphenhydramine

59
Q

Long term inhaled
steroids increase risk
for

60
Q

Most common cause of
UTI

61
Q

Primary antibiotics for
UTI

A

Nitrofurantoin and Fosfomycin

62
Q

Nerve associated with
sinus arrhythmia

A

Vagus nerve

63
Q

Drug associated with
development of renal
cell carcinoma

A

Aspirin, Ibuprofen, Paracetamol

64
Q

Smoking increases risk
for kidney cancer by
how much

A

2 times the risk

65
Q

Bruising in flanks of
hemorrhagic
pancreatitis

A

Grey-Turner sign

66
Q

Scleroderma

A
  • woman with thickened skin, tight
    fingers “sclerodactyly
  • Raynaud’s phenomenon or digital
    pitting scars – dark shiny skin on
    distal phalanges of both arms
  • Associated with sclerodactyly
  • Associated with Vitamin D
    deficiency