Bullae in diabetic persons

Question 1

Clinical presentation

Answer 1

Diabetics of any age

• no known relationship between bullae development and glycemic control
• usually get crops of bullae on lower legs and feet that develop overnight
• asymptomatic
• bullae rupture in a week but take months to heal fully

Question 2

Histology

Answer 2

intra or subepidermal bullae with minimal inflammation. No abnormalities on DIF

Question 3

Treatment

Answer 3

Can compress ulcers with tepid aline solution but generally resolves on its own