Bugs & drugs (Antivirals) Flashcards
1
Q
Treat influenza
A
Zanamivir, Oseltamivir (inh NA)
2
Q
Ribavirin treats?
A
RSV, Chronic HCV
3
Q
Treat HSV & VZV
A
Acyclovir or Valacyclovir (better oral bioavailability)
These drugs must be activated by viral thymidine kinase –> then they inh viral DNA polymerase
*Guanosine analog
*For acyclovir resistant HSV, use Foscarnet
4
Q
Treat herpes zoster
A
Famciclovir
5
Q
Acyclovir can be used for?
A
Oral or genital HSV lesions, VZV, weak activity against EBV, HSV encephalitis, prophylaxis in immunocompromised pts
6
Q
Treat CMV
A
Ganciclovir.. If it fails, use Foscarnet or Cidofovir