BUG - DRUG Pairings Flashcards
1st Generation Cephalosporin
1st: Cefazolin (IV). Cephalexin (PO).
2nd Generation Cephalosporins
2nd: Cefuroxime, Cefoxitin, Cefprozil
3rd Generation Cephalosporins
3rd: Ceftriaxone, Cefixime, Cefotaxime, Ceftazidime (more gram (-) less gram +)
4th Generation Cephalosporins
4th: Cefepime
MSSA Coverage:
Everything except: PenG/VK, Amoxicillin (w/o clav), Ceftazidime. (other 3rd gen cefs OK.)
MRSA Coverage:
Vancomycin, linezolid.
Community aquired:
CA: clindamycin, SMX-TMP, Tetracyclines. (+ vanco/linezolid)
Enterococcus Coverage.
Penicillin, amoxicillin, amoxiclav, NO CEPHALOSPORINS. Vanco, Aminoglycoside (SYNERGY), maybe FQ’s.
Strep Pneumo Coverage
All Betalactams - except ceftazidime (+/-), cloxacillin (-), cephalexin/cefazolin (+/-).
Strep pyogenes/ other strep (non.penumo) coverage.
All betalactams (except ceftazidime (+/-), cloxacillin (+/-).
H.influenza + M. Catarhallis Coverage.
Amoxi. Amoxiclave. Cephalexin (+/-), 2nd,3rd,4th gen cephs. FQs, AG’s, SMX-TMP, clarithro/azithro, tetracyclines.
Proteus, ecoli, klebsiella coverage.
Amoxi. Amoxiclav. Cephalexin (+/-), 2nd,3rd,4th gen cephs. FQs, AG’s, SMX-TMP, tetracyclines.
SPACE Bugs coverage. (6)
3rd gen cephs (+/-), except ceftazidime (+), piptazo, cefepime, imipenem/meropenem.
Pseudomonas Coverage (6)
Pip/tazo, imipenem/meropenem, ceftazidime, cefepime, cipro (the only PO), Gentamicin/Tobramycin,
Oral anaerobe coverage
All penicilins except cloxacillin, 2nd,3rd (NOT ceftazidime), 4th gen Cephs, imipenem/meropenem, clindamycin, levo/moxi, metro. (SIMILAR pattern to gram +. Those which have gram + effects OK)
