Anti Epileptic Drugs

Question 1

AEDs which are associated w/ hepatotoxicity.

Answer 1

Children Prefer Vodka
CBZ PHT VPA

Question 2

AEDs are associated w/ severe skin rash, moderate, mild.

Answer 2

PCL - Phenytoin Carb Lamotrigine
POC - Phenobarb Oxycarbazepine Clobazem
VGTL - Valproic Gabapentin Topiramate Leviceteram

Question 3

AED’s are common to all AED’s?

Answer 3

Somnolence, sleepiness, dizziness, blurred vision.

Question 4

AED which can worsen vision.

Answer 4

Topiramate. (PEER into someones eyes)

Question 5

AED’s are best in elderly.

Answer 5

Gabapentin Lamotrigine, valproic Acid (grandpa loves anal)

Question 6

AED concerned about with asians.

Answer 6

Asians: Carbamazepine use due to HLAB allele = higher risk of SJS and TEN (asians and CARs= bad combo.)

Question 7

AED associated w/ weight GAIN.

Answer 7

Gain weight - valproic acid (drinking sugar all day!)

Question 8

AED associated w/ weight LOSS.

Answer 8

Lose weight - topiramate - sleepy people do not eat food!

Question 9

AEDs which cause osteoporosis

Answer 9

Osteopenia: F..F AC! (FUCK) = PhenoBarbitol + Phenytoin + valproic Acid + carbamazepine,

Question 10

AED which causes Hirsuitism.

Answer 10

Phenytoin

Question 11

AED enzyme inducers.

Answer 11

inducers: Carbamazepin Phenytoin Phenobarb = CPP = canada pension plan = autoinducing

Question 12

Aed which causes hair loss.

Answer 12

Hair loss: Valproic

Question 13

AED which causes menstrual irregularities.

Answer 13

VPA

Question 14

AED which cause Hepatotoxicity.

Answer 14

Valproic acid

Question 15

Adverse effects of VPA

Answer 15

STHW GHETTO:
Sedation, Teratogenicity, Hepatotoxicity, Weight gain, Good for elderly, hairloss, endocrine problem (menstrual irregularities), Tremor, thrombocytopenia, osteopenia.

Question 16

AED with worst sleepness, cognitive dysfunciton.

Answer 16

Topiramate (dopamax)

Question 17

AEDs which cause arrythmias (3)

Answer 17

Arrythmia = PLUCK a heartstring = Phenytoin, Lacosamide, Carbamazepine

Question 18

AED associated with hyponatremia.

Answer 18

salty C-Ocks = COX = Carbamazepine + Oxycarbazepine

Question 19

AED associated with Metabolic Acidosis.

Answer 19

Metabolic acidosis = Topiramate = Top Metabolic

Question 20

AED associated with tremor.

Answer 20

Tremor = Valproate = too much syrup = sugar = tremor

Question 21

AED associated with thrombocytopenia

Answer 21

Thrombocytopenia = Syrup looks like blood! = throbocytopenia

Question 22

AED associated with Leukopenia.

Answer 22

Leukopenia = Lucky CaP = leuko = Carbamazepine + Phenytoin

Question 23

First line agents for JME.

Answer 23

Violent Lambs topple lemmings.
Valproic Acid.
(2nd) Lamotrigine, Topiramate, Levitiracetam.

Question 24

First line agents for Myoclonic Seizure.

Answer 24

Violent lambs topple lemmings constantly.
VPA.
(2nd) Lamotrigine, Topiramate, Levitiracetam, Clobazem.

Question 25

First line agents for Clonic/Tonic Seizure.

Answer 25

CLaP the CliT.
(1st) Carbamazepine, Lamotrogine, VPA, Phenytoin.
(2nd) Clobazem, levitiracetam, topiramate.

Question 26

First line agents for absence.

Answer 26

Ethosuximibe.
ClobLL Top V
Clobazem, Lamotrigine, Levitiracetam, Topiramate, VPA.

Question 27

First line agents for Simple/Complex partial seizures.

Answer 27

Complex Carbs, Lead (to) Fulfilling Lives
Carbamazepine
Lamotrigine, Phenytoin, Levitiracetam.

Question 28

Minimum duration seizure free to get drivers license.

Answer 28

0.5-1 year.